Results 151 to 160 of about 4,324,517 (401)

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

open access: yesAdvanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir   +7 more
wiley   +1 more source

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

open access: yesAdvanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang   +8 more
wiley   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

open access: yesAdvanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du   +5 more
wiley   +1 more source

Number Express: a Digital Game to Improve Early Numeracy

open access: diamond, 2023
Nicoletta Perini   +4 more
openalex   +2 more sources

Game Changer: Investing in Digital Play to Advance Children's Learning and Health [PDF]

open access: yes, 2009
Based on a literature review and interviews with digital learning experts, explores how digital games can foster skills and knowledge for better academic performance and health.
Ann My Thai   +3 more
core  

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

open access: yesAdvanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li   +10 more
wiley   +1 more source

Serious Game Promotes the Cultural Transmission of Agricultural Heritage Mulberry-Dyke and Fishpond System

open access: yesSAGE Open
The Zhejiang Huzhou Mulberry Base Pond System (HMBPS) is a complex and comprehensive “Globally Important Agricultural Heritage System (GIAHS).” Current research on the conservation of HMBPS predominantly focuses on agriculture, ecology, and land ...
Ning Gao   +5 more
doaj   +1 more source

Simlandscape: serious gaming in participatory spatial [PDF]

open access: yes
In an attempt to improve support for contemporary spatial planning practice, Simlandscape has been developed. In this document the development of Simlandscape as ¿serious game¿ in digital form is described.
Ligtenberg, A.   +3 more
core  

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