Results 91 to 100 of about 37,573 (262)

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Editorial: User states in extended reality media experiences for entertainment games

Frontiers in Virtual Reality, 2023
Phil Lopes, Jan-Niklas Voigt-Antons, Jaime Garcia, David Melhart   +3 more
doaj   +1 more source

Eastern European gaming cultures. Case studies: Romania and Bulgaria

Sociologie Românească, 2009
Digital games are a complex social and technological phenomenon that is situated in cultures and societies. Current academic efforts in the field of digital games analyze the realities of the Western countries, where the market on digital games is highly
Elena Policov, Adriana Ţăruş, Lyuba Yordanova, Alexander Kempf   +3 more
doaj  

Perceptions and factors affecting the adoption of digital games for engineering education: a mixed-method research. [PDF]

Int J Educ Technol High Educ, 2023
Udeozor C, Russo-Abegão F, Glassey J.
europepmc   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

Digital games and virtual reality applications in child abuse: A scoping review and conceptual framework. [PDF]

PLoS One, 2022
Asadzadeh A, Shahrokhi H, Shalchi B, Khamnian Z, Rezaei-Hachesu P.   +4 more
europepmc   +1 more source

Visualizing and Quantifying Impact with Mechanochromic Sensing Paints Based on Self‐Assembled Polydiacetylene‐Silk Core‐Shell Vesicles

Advanced Science, EarlyView.
Tracking physical impacts is important in many fields. Self‐assembled microparticles made from polydiacetylene and silk fibroin that change color from blue to red when hit can provide an alternative approach to traditional mechanical transducers, quantitatively visualizing impact with responses ranging from <100 to 770 N.
Marco Lo Presti, Giulia Guidetti, Elisabetta Ruggeri, Terri Lyne Carrington, Fiorenzo G. Omenetto   +4 more
wiley   +1 more source

Editorial: Digital Games and Mental Health. [PDF]

Front Psychol, 2021
Kowert R, Ferguson CJ, Fletcher PC, Rusch D.   +3 more
europepmc   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Subjective experiences and perceptions of learning a second language through digital games: A case study of Chinese college students. [PDF]

Front Psychol, 2022
Xiao X, He G.
europepmc   +1 more source