Results 111 to 120 of about 705,935 (306)

Interactive Food and Beverage Marketing: Targeting Children and Youth in the Digital Age [PDF]

, 2007
Looks at the practices of food and beverage industry marketers in reaching youth via digital videos, cell phones, interactive games and social networking sites.

core  

Coupled Above‐ and Belowground Ecosystem Stability Worldwide

Advanced Science, EarlyView.
Are the worlds above and below our feet in sync? This global exploration reveals an entangled fate between above‐ and belowground ecosystem stability. It identifies arid regions as hotspots for this coupling and highlights temperature stability as a vital safeguard for maintaining ecosystem balance across our warming planet.
Zexin Meng, Huiwen Li, Yiping Wu, Peter B. Reich, Nico Eisenhauer, Diego Abalos, Daniel Revillini, Shuguang Liu, Wende Yan, Ji Chen, Alexey Voinov, Zhifeng Yang, Ying‐Ping Wang, Fubo Zhao, Linjing Qiu, Jingfeng Xiao, Shantao An, Guopeng Liang, Manuel Delgado‐Baquerizo   +18 more
wiley   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Creating a Playable Academic Edition of Mourning Dove’s Cogewea or How Games can Decolonize

KULA, 2019
Digital games have the tools and capacity to build interactive worlds that can both share knowledge and decolonize. Even though games have been accused of reinforcing white supremacist systems that tend to privilege profit over humanity, digital games by
Sara Humphreys
doaj   +1 more source

Development and Validation of a Questionnaire to Measure Perceptions of Freedom of Choice in Digital Games

International Journal of Serious Games, 2016
The purposes of this study were (a) to develop a valid and reliable questionnaire using both the structural characteristics of digital games and students perceptions of the concept of freedom of choice in digital games, (b) to validate items to be used ...
Sotiris Kirginas, Dimitris Gouscos
doaj   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

The advantages and limitations of digital games in children’s health promotion

Finnish Journal of eHealth and eWelfare, 2014
Childhood is an important period for forming the foundation for future health and well-being, and there is need for new methods for these health promotion purposes.
Heidi Parisod, Minna Aromaa, Lotta Kauhanen, Kai Kimppa, Camilla Laaksonen, Ville Leppänen, Anni Pakarinen, Jouni Smed, Sanna Salanterä   +8 more
doaj  

Learner autonomy development through digital gameplay [PDF]

Digital Culture & Education, 2011
Playing digital games is undeniably a popular leisure activity, and digital gaming is also gaining academic attention and recognition for enhancing digital literacies and learning motivation.
Alice Chik
doaj  

Potencial Expressivo nos Jogos Indie e Gamearte: Breve análise dos jogos Flower e Journey

Obra Digital, 2013
Os jogos digitais tem se apresentado como um meio com grande potencial expressivo e comunicacional, contrariando a visão tradicional que considera os games como uma mídia que deve ser usada apenas para o entretenimento. Nos jogos independentes – indies –
Bruno Henrique De Paula, Hermes Renato Hildebrand   +1 more
doaj   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source