Results 41 to 50 of about 1,760,881 (298)
Current state of e-services in Saudi Arabia: the case of intermediaries in facilitating government services in Madinah city [PDF]
, 2009 The government of Madinah has launched ‘Khdamatec’ electronic Offices (e-Offices) concept under their national electronic Government (e-Government) modernisation agenda to facilitate service delivery to citizens and seamless interaction to communicate ...
Al-Sobhi, F, Kamal, M, Weerakkody, V
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
State Digital Policy: Risks and Opportunities
Современная наука и инновацииThe purpose of the article is to study possible risks and opportunities in the field of state digital policy. The primary task in this direction was to study the concepts of ―digitalization‖, ―digital policy‖, ―digital economy‖.
M. E. Levchenko +2 more
doaj +1 more source
Eventuality issues of digital transformation of socio-economic systems
E-Management, 2023 The article examines the possible prospects for the development of the Russian economy due to the intensification of the processes of digital transformation.
N. S. Kozyr
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Game Changer: Investing in Digital Play to Advance Children's Learning and Health [PDF]
, 2009 Based on a literature review and interviews with digital learning experts, explores how digital games can foster skills and knowledge for better academic performance and health.
Ann My Thai +3 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Enhancing Sensitivity Classification with Semantic Features using Word Embeddings [PDF]
, 2017 Government documents must be reviewed to identify any sensitive information they may contain, before they can be released to the public. However, traditional paper-based sensitivity review processes are not practical for reviewing born-digital ...
B Fung +8 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source