Results 41 to 50 of about 568,230 (309)
Advancing Australia as a digital economy: an update to the national digital economy strategy [PDF]
, 2013 The Government’s 2011 National Digital Economy Strategy (the 2011 NDES) set the goal of Australia becoming a leading digital economy by 2020. In doing so, it nominated eight goals to position Australia as a world leader in broadband connectivity and the ...
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
New models for digital government: the role of service brokers in driving innovation [PDF]
, 2014 Executive summary Digital Government strategies are being rolled out in many Australian and international jurisdictions, ushering in a fundamentally different approach to the design and delivery of public sector services.
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State Digital Policy: Risks and Opportunities
Современная наука и инновацииThe purpose of the article is to study possible risks and opportunities in the field of state digital policy. The primary task in this direction was to study the concepts of ―digitalization‖, ―digital policy‖, ―digital economy‖.
M. E. Levchenko +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Explicating the Process of Digital Government Programmes: Bridging Research and Practice
, 2022 Achieving the successful delivery of digital transformation projects and programmes has become a critical agenda for most government organisations.
Cha, J.
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Digital Government and Health System Performance: Does Digitalization Improve the Effectiveness of Health Expenditure? [PDF]
Health Economics and Management ReviewDigital transformation has become a critical driver of public sector efficiency and health system performance, yet its role in enhancing the effectiveness of health expenditure remains insufficiently understood.
Larysa HRYTSENKO +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
, 2022 Media activities related to digitalization are present in many aspects of daily life. Since the PSBB was passed on March 15, 2021, the community has been afected by the Covid-19 pandemic.
Suprayitno, Degdo +3 more
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