Results 81 to 90 of about 13,034,687 (321)

An umbrella review on how digital health intervention co-design is conducted and described

npj Digital Medicine
Co-design has been suggested to improve intervention effectiveness and sustainability. However, digital health intervention co-design is inconsistently reported.
A. Kilfoy, T. Hsu, Charlotte Stockton-Powdrell, Pauline Whelan, Charlene H Chu, Lindsay Jibb   +5 more
semanticscholar   +1 more source

Using Formative Research and Audience-Centric Intelligence to Develop the #JustBe Digital Magazine: An mHealth Strategy to Improve Adolescent Sexual Health [PDF]

, 2017
Digital strategies may help to overcome challenges in providing contraception education to overlooked and key sub-populations (older teens, ethnic minority youth, LGBTQ youth, high school dropouts and males).
Cruz, Jorge, Cruz, Maribel, Edwards, Sharon, Johnson-Baker, Kimberly, Swain-Ogbonna, Honora I, Tortolero, Susan R.   +5 more
core   +2 more sources

Acceptability of artificial intelligence (AI)-enabled chatbots, video consultations and live webchats as online platforms for sexual health advice [PDF]

, 2020
Objectives Sexual and reproductive health (SRH) services are undergoing a digital transformation. This study explored the acceptability of three digital services, (i) video consultations via Skype, (ii) live webchats with a health advisor and (iii ...
Bayley, J., Bayley, J., Graham, C.A., Graham, C.A., Kidsley, S., Kidsley, S., Llewellyn, C., Llewellyn, C., Nadarzynski, T., Nadarzynski, T.   +9 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

SONAR, a nursing activity dataset with inertial sensors

Scientific Data, 2023
Accurate and comprehensive nursing documentation is essential to ensure quality patient care. To streamline this process, we present SONAR, a publicly available dataset of nursing activities recorded using inertial sensors in a nursing home.
Orhan Konak, Valentin Döring, Tobias Fiedler, Lucas Liebe, Leander Masopust, Kirill Postnov, Franz Sauerwald, Felix Treykorn, Alexander Wischmann, Stefan Kalabakov, Hristijan Gjoreski, Mitja Luštrek, Bert Arnrich   +12 more
doaj   +1 more source

Recommendations to advance digital health equity: a systematic review of qualitative studies

npj Digital Medicine
The World Health Organisation advocates Digital Health Technologies (DHTs) for advancing population health, yet concerns about inequitable outcomes persist.
S. Wilson, C. Tolley, R. Mc Ardle, Lauren Lawson, E. Beswick, N. Hassan, R. Slight, Sarah P. Slight   +7 more
semanticscholar   +1 more source

The ethics of digital well-being: a multidisciplinary perspective [PDF]

This chapter serves as an introduction to the edited collection of the same name, which includes chapters that explore digital well-being from a range of disciplinary perspectives, including philosophy, psychology, economics, health care, and education ...
A Abukonna, A Alexandrova, A Elder, A Ferretti, A Jobin, A Orben, A Orben, AM Wood, B Fröding, B Goldacre, B Mittelstadt, C Burr, C Burr, C Woodard, CD Ryff, CJ Ferguson, D Hausman, D Howard, D Jeske, D Kahneman, D Lupton, D Parfit, DA Ellis, DB Dwyer, DM Haybron, DM Haybron, E Brynjolfsson, E Diener, E Lin, E Palm, ED Diener, F Greaves, FA Huppert, G Fletcher, I Robeyns, J Garde-Hansen, J Pugh, J Torous, J Williams, JN Craig, JW Galbraith, K Binmore, K Layous, K Sterelny, L Floridi, L Floridi, L Floridi, LK Ma, LW Sumner, M Bishop, M Burke, M Csikszentmihalyi, M Nussbaum, M Themistocleous, MC Nussbaum, MEP Seligman, MR Munafò, MR Munafò, N Kosmyna, NC Manson, NH Frijda, NS Kim, P Henson, P Stokes, P Verduyn, R Challen, R Crisp, R Sharp, R Yost-Dubrow, RA Calvo, RA Calvo, RJ Watson, RM Ryan, RM Ryan, RR Faden, S Allen, S Ghafur, S Leigh, S Sterckx, S Vallor, S Vallor, T Burns, T Hills, T Justinia, TK Mackey, TL Beauchamp, V Tiberius   +86 more
core   +1 more source

Influences on the Uptake of and Engagement With Health and Well-Being Smartphone Apps: Systematic Review [PDF]

, 2020
Background: The public health impact of health and well-being digital interventions is dependent upon sufficient real-world uptake and engagement. Uptake is currently largely dependent on popularity indicators (eg, ranking and user ratings on app stores),
Brown, Jamie, Chadborn, Tim, Jones, Andy, Naughton, Felix, Szinay, Dorothy   +4 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Understanding inherent influencing factors to digital health adoption in general practices through a mixed-methods analysis

npj Digital Medicine
Extensive research has shown the potential value of digital health solutions and highlighted the importance of clinicians’ adoption. As general practitioners (GPs) are patients’ first point of contact, understanding influencing factors to their digital ...
Lisa Weik, Leonard Fehring, A. Mortsiefer, Sven Meister   +3 more
semanticscholar   +1 more source