Results 81 to 90 of about 12,697,710 (368)

Telemedicine, e-Health, and Digital Health Equity: A Scoping Review

Clinical Practice and Epidemiology in Mental Health
Background: With the progressive digitization of people's lives and in the specific healthcare context, the issue of equity in the healthcare domain has extended to digital environments or e-environments, assuming the connotation of “Digital Health ...
D. Petretto, Gian Pietro Carrogu, L. Gaviano, Roberta Berti, Martina Pinna, Andrea Domenico Petretto, Roberto Pili   +6 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Factors influencing digital health literacy among older adults: a scoping review

Frontiers in Public Health
Background The growth of digital technology, represented by the development of the Internet, has become popular among older adults. Implying digital health literacy on older adults also affects their ability to use digital technology to search, browse ...
Zhen Shi, Xixi Du, Juan Li, Rongting Hou, Jingxuan Sun, Thammarat Marohabutr   +5 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

SONAR, a nursing activity dataset with inertial sensors

Scientific Data, 2023
Accurate and comprehensive nursing documentation is essential to ensure quality patient care. To streamline this process, we present SONAR, a publicly available dataset of nursing activities recorded using inertial sensors in a nursing home.
Orhan Konak, Valentin Döring, Tobias Fiedler, Lucas Liebe, Leander Masopust, Kirill Postnov, Franz Sauerwald, Felix Treykorn, Alexander Wischmann, Stefan Kalabakov, Hristijan Gjoreski, Mitja Luštrek, Bert Arnrich   +12 more
doaj   +1 more source

An umbrella review on how digital health intervention co-design is conducted and described

npj Digital Medicine
Co-design has been suggested to improve intervention effectiveness and sustainability. However, digital health intervention co-design is inconsistently reported.
A. Kilfoy, T. Hsu, Charlotte Stockton-Powdrell, Pauline Whelan, Charlene H. Chu, Lindsay Jibb   +5 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Jefferson Digital Commons quarterly report: October-December 2018 [PDF]

, 2019
This quarterly report includes: Articles Dissertations From the Archives Grand Rounds and Lectures Industrial Design Capstones Journals and Newsletters LabArchives Launch Masters of Public Health Capstones Posters Reports Videos What People are Saying ...
Copeland, LIBT, James, Duinkerken, MSI, Kelsey   +1 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Using Formative Research and Audience-Centric Intelligence to Develop the #JustBe Digital Magazine: An mHealth Strategy to Improve Adolescent Sexual Health [PDF]

, 2017
Digital strategies may help to overcome challenges in providing contraception education to overlooked and key sub-populations (older teens, ethnic minority youth, LGBTQ youth, high school dropouts and males).
Cruz, Jorge, Cruz, Maribel, Edwards, Sharon, Johnson-Baker, Kimberly, Swain-Ogbonna, Honora I, Tortolero, Susan R.   +5 more
core   +2 more sources