Results 101 to 110 of about 1,709,733 (265)

The Magnifying Glass and the Kaleidoscope. Analysing Scale in Digital History and Historiography [PDF]

open access: yes, 2018
What is the meaning of scale in historical writings and migration narratives? To what extent can digital tools and methods assist the detection of scale-related patterns in these categories of documents?
ARMASELU, Florentina
core  

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Keynote lecture: The Hybrid Historian - Historical Research in the Digital Age

open access: yes, 2020
In the past decade, we have witnessed a shift from technological determinism to more attention to the methodological and epistemological changes in historical research which the digital turn has brought about.
ZAAGSMA, Gerben
core  

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Ob Werkzeugkoffer, Werkstatt oder Baumarkt: offene, community-kuratierte Tool Registries mit Wikidata

open access: yes
Isabell Trilling, Till Grallert, Jascha Schmitz In diesem Blogbeitrag wird das an der HU angesiedelte Projekt zur Erstellung eines offenen, community-kuratierten Werkzeugverzeichnisses für die Digital Humanities als Kollaboration von “Kompetenzwerkstatt ...
Digital History Berlin (Redaktion)
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Sebastian Kawanami-Breu, Johan Malmstedt: The Similarity Engine. Steps Towards a Media History of Vector Modeling

open access: yes
Our project revolves around the historical epistemology of vector space models, which we attempt to situate within a larger history of the human quest to measure, quantify, and analyze "similarity".
Digital History Berlin (Redaktion)
core   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Elena Suárez Cronauer: Netzwerkanalyse und Data Feminism. Frauenbriefe im frühromantischen Briefnetzwerk

open access: yes
Wie können marginalisierte Gruppen mit Methoden der historischen Netzwerkanalyse untersucht werden, ohne dass biases in den Quellen, die sich in den Daten widerspiegeln, unreflektiert wiederholt und somit weitergetragen werden?
Digital History Berlin (Redaktion)
core   +1 more source

Toward a Praxis of Critical Digital Sport History

open access: yes, 2017
Exploring praxis as a key construct, this article disputes the understandings of digital history as a relatively recent phenomena by providing an alternative narrative of digital history’s development.
Guiliano, Jennifer, Jennifer Guiliano
core   +1 more source

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