Results 91 to 100 of about 436,970 (323)

A Decade in Digital Humanities [PDF]

open access: yes, 2016
The paper reviews the meaning and development of digital humanities giving the examples of work published in various DH areas. The paper discusses what using these technologies means for the humanities, giving recommendations that can be useful across ...
Terras, MM
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Sustaining Digital Humanities Collections: Challenges and Community-Centred Strategies

open access: yesInternational Journal of Digital Curation, 2020
Since the advent of digital scholarship in the humanities, decades of extensive, distributed scholarly efforts have produced a digital scholarly record that is increasingly scattered, heterogeneous, and independent of curatorial institutions.
Katrina Simone Fenlon
doaj   +1 more source

ELAN as flexible annotation framework for sound and image processing detectors [PDF]

open access: yes, 2010
Annotation of digital recordings in humanities research still is, to a largeextend, a process that is performed manually. This paper describes the firstpattern recognition based software components developed in the AVATecH projectand their integration in
Auer, E.   +7 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

GraphEidos: A Dataset of Visual Rhetoric in Digital Humanities

open access: yesJournal of Open Humanities Data
This data article introduces GraphEidos, a new open-access dataset that documents how visuals have been used and discussed in digital humanities (DH) journal publications. The dataset covers various forms of visual representations, their captions, and in-
Rongqian Ma, Kai Li, Ranvir Singh Virk
doaj   +1 more source

Art History and the Digital Humanities: [PDF]

open access: yes, 2016
Invited response to "Hubertus Kohle, "Kunstgeschichte und Digital Humanities. Einladung zu einer Debatte/Art History and the Digital Humanities.
Max Marmor
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Interdisciplinary Collaboration in Studying Newspaper Materiality

open access: yesDigital Humanities in the Nordic and Baltic Countries Publications, 2019
This paper presents a collaboration between computer scientists, linguists and historians studying the material aspects of newspapers and developing a tool for that purpose.
Eetu Mäkelä   +5 more
doaj   +1 more source

Digital Sandbox: Playing with Public Humanities [PDF]

open access: yes, 2014
poster abstractWe developed and led a daylong workshop on the digital humanities that took place at IUPUI on August 15, 2013. This project grew out of a spring 2013 digital humanities course taught by Dr.
Crosby, Christine   +3 more
core  

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