Results 91 to 100 of about 3,006,454 (408)

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Corpus Linguistics and Digital Humanities. Intersecting Paths. A Case Study from Twitter

open access: yesAmérica Crítica, 2020
In this paper I aim at critically discussing the role of Corpus Linguistics within the field of Digital Humanities. I posit that the accessible and user-friendly tools of Corpus Linguistics are an optimal resource for scholars within the Humanities and ...
Angela Zottola
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

DHI Digital Projects Showcase Program [PDF]

open access: yes, 2016
A program of the inaugural DHI Digital Projects Showcase, held in the Student Union on November 2 ...
University of North Florida Digital Humanities Initiative
core   +1 more source

Digital Public Humanities [PDF]

open access: yes, 2017
Syllabus for graduate-level course in Digital Public Humanities taught by Jim McGrath (postdoctoral fellow in Digital Public Humanities). Course is part of Brown's Public Humanities M.A.
Jim McGrath
core   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Teaching Libraries zwischen Vermittlung fachwissenschaftlicher Informationskompetenz und der Unterstützung einer Propädeutik für die Digital Humanities

open access: yeso-bib. Das offene Bibliotheksjournal, 2017
Der Beitrag geht von der Beobachtung aus, dass Bibliotheken bisher zwar die Themen E‑Science und Forschungsdaten in ihre Überlegungen hinsichtlich spezifischer Angebote zur Informationskompetenz einbezogen haben. Aber obwohl Bibliotheken über ein breites
Marcus Schröter
doaj   +1 more source

The stochastic digital human is now enrolling for in silico imaging trials -- Methods and tools for generating digital cohorts [PDF]

open access: yesarXiv, 2023
Randomized clinical trials, while often viewed as the highest evidentiary bar by which to judge the quality of a medical intervention, are far from perfect. In silico imaging trials are computational studies that seek to ascertain the performance of a medical device by collecting this information entirely via computer simulations.
arxiv  

The Digital Humanities [PDF]

open access: yes, 2015
AbstractIn the last 25 years digital technologies have changed the humanities. The question is: by how much? Is the digital revolution transforming the humanities intellectually? Or has it just sped up processes and access in ways that are certainly faster but not essentially different?
Arne Jarrick, Poul Holm, Dominic Scott
openaire   +2 more sources

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

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