Results 101 to 110 of about 3,232,610 (341)
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
This paper addresses the relationship between Digital Libraries (DL) and Digital Humanities (DH) with a special focus on global access to knowledge. An overview DL & DH and their interconnections are described.
Widad El Hadi
doaj
Numerous digital media repositories have been set up during recent decades, each containing plenty of data about historic cityscapes. In contrast, digital 3D reconstructions of no longer extant cityscapes have so far almost solely been performed for ...
Sander Münster +9 more
doaj +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
DIGITAL HUMANITIES IN HIGHER EDUCATION SYSTEM OF CANADA
The urgency of the article is due to the increased impact of information and communication technologies on research in the field of socio-humanitarian cycle sciences, which led to the emergence of interdisciplinary direction of research and projects ...
Olena Voskoboinikova-Huzieva
doaj +1 more source
Corpus Linguistics and Digital Humanities. Intersecting Paths. A Case Study from Twitter
In this paper I aim at critically discussing the role of Corpus Linguistics within the field of Digital Humanities. I posit that the accessible and user-friendly tools of Corpus Linguistics are an optimal resource for scholars within the Humanities and ...
Angela Zottola
doaj +1 more source
Digital Humanities in the Anthropocene [PDF]
This keynote address for the 2014 Digital Humanities conference is a practitioner’s talk, and—though the abstract belies it—an optimistic one. I take as given the evidence that human beings are irrevocably altering the conditions for life on Earth and that, despite certain unpredictabilities, we live at the cusp of a mass extinction.
openaire +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
This open access book deals with cultural and philosophical aspects of artificial intelligence (AI) and pleads for a “digital humanism”. This term is beginning to be en vogue everywhere. Due to a growing discontentment with the way digitalization is being used in the world, particularly formulated by former heroes of Internet, social media and search ...
Nida-Rümelin, Julian +1 more
openaire +3 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source

