Results 51 to 60 of about 36,964,672 (289)

Strategic safeguarding: A game theoretic approach for analyzing attacker-defender behavior in DNN backdoors

open access: yesEURASIP Journal on Information Security
Deep neural networks (DNNs) are fundamental to modern applications like face recognition and autonomous driving. However, their security is a significant concern due to various integrity risks, such as backdoor attacks.
Kassem Kallas   +3 more
doaj   +1 more source

Identity reconstruction and digital addiction: the paradoxical mechanism of digital inclusion among the new generation of older adults

open access: yesFrontiers in Psychology
IntroductionAgainst the backdrop of population aging and rapid digitalization in China, the new generation of older adults faces a growing paradox of digital inclusion.
Haibei Chen   +2 more
doaj   +1 more source

DIGITAL IDENTITY

open access: yesScientific Annals of the “Alexandru Ioan Cuza” University, Iaşi. New Series SOCIOLOGY AND SOCIAL WORK Section, 2021
The text aims to bring forward a topical issue, that of digital identity. Based on a series of international  discussions (Davos Forum, EU) but also in the context of recent announcements   in  the  field  of  new  technologies  (the  announcement   made  by  M.
openaire   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Analysis of digital evidence in identity theft investigations [PDF]

open access: yes, 2012
Identity Theft could be currently considered as a significant problem in the modern internet driven era. This type of computer crime can be achieved in a number of different ways; various statistical figures suggest it is on the increase.
Angelopoulou, Olga
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

No Peace After Death? The Impact of AI-Driven Memorial Chatbots on Privacy and Data Protection

open access: yesInformation
This paper examines the profitable digital afterlife industry (DAI), whose aim is to monetize the digital remains of departed internet users. Among the different services offered by such an industry, attention is drawn to AI and humanoid robots that ...
Jacopo Ciani Sciolla, Ugo Pagallo
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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