Results 61 to 70 of about 36,964,672 (289)

SIBERIA: A Self-Sovereign Identity and Multi-Factor Authentication Framework for Industrial Access

Applied Sciences
The growing need for secure and privacy-preserving identity management in industrial environments has exposed the limitations of traditional, centralized authentication systems.
Daniel Paredes-García, José Álvaro Fernández-Carrasco, Jon Ander Medina López, Juan Camilo Vasquez-Correa, Imanol Jericó Yoldi, Santiago Andrés Moreno-Acevedo, Ander González-Docasal, Haritz Arzelus Irazusta, Aitor Álvarez Muniain, Yeray de Diego Loinaz   +9 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Privacy by Design Architecture Composed of Identity Agents Decentralizing Control over Digital Identity

, 2020
Proposed is an identity architecture that satisfies the principles of privacy by design, decentralizes control over digital identity from providers to users, mitigates breach and impersonation risks, and reduces dependency on remote access passwords. The
Cavoukian, Ann, Anderson-Priddy, Alan, Toth, Kalman C.   +2 more
core   +1 more source

Creating Digital Identity for Arabic National Libraries from Content Analysis of Missions & Vision Statements Using Machine Learning Algorithms. [PDF]

المجلة المصرية لعلوم المعلومات
Creating Digital Identity for Arabic National Libraries from Content Analysis of Missions & Vision Statements Using Machine Learning Algorithms.This study explores the utilization of ML content analysis algorithms to create a robust digital identity for ...
مؤمن سيد النشرتي النشرتيي
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Digital Identity 3.0: The Platform for People [PDF]

, 2015
Developed economies are moving from an economy of corporations to an economy of people. More than ever, people produce and share value amongst themselves, and create value for corporations through co-creation and by sharing their data.
Mertens, Willem, Rosemann, Michael
core   +1 more source

Identity Processes in Adulthood: Diverging Domains

, 2015
Patterns of identity formation were analyzed in a longitudinal framework, from ages 27 to 36 and then to 42 years of age. Information from all 3 ages was available for 197 participants (100 women, 97 men). A variation of Marcia’s (1966) Identity Status
Kokko, Katja, Pulkkinen, Lea, Fadjukoff, Päivi   +2 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source