Results 51 to 60 of about 2,234,079 (295)

Brain Functional Plasticity Driven by Career Experience: A Resting-State fMRI Study of the Seafarer

Frontiers in Psychology, 2017
The functional connectome derived from BOLD resting-state functional magnetic resonance imaging data represents meaningful functional organizations and a shift between distinct cognitive states.
Nizhuan Wang, Nizhuan Wang, Weiming Zeng, Yuhu Shi, Hongjie Yan   +4 more
doaj   +1 more source

Analyzing Digital Image by Deep Learning for Melanoma Diagnosis [PDF]

, 2019
Image classi cation is an important task in many medical applications, in order to achieve an adequate diagnostic of di erent le- sions. Melanoma is a frequent kind of skin cancer, which most of them can be detected by visual exploration ...
A Victor, AF Jerant, BM Devassy, F Nachbar, L Yu, M Ruela, MH Jafari, N Nida, S Bakheet, V Yadav   +9 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Individual Tree Crown Delineation in Heterogeneous Urban Environments Using High-Resolution Airborne Imagery

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Urban trees are crucial to mitigate the increasing urban temperatures caused by climate change. Tree inventories, which are useful for urban planning and tree management, are mostly based on expensive and incomplete in situ measurements. Freely available
Oliver Schutte, Moritz Lucas, Bjorn Waske   +2 more
doaj   +1 more source

Facial aging simulation via tensor completion and metric learning

IET Computer Vision, 2017
Facial aging simulation is one of the most challenging issues in automatic machine based face analysis, where the most essential requirements are (i) human identity should remain stable in texture synthesis and (ii) the texture synthesised is expected to
Heng Wang, Di Huang, Yunhong Wang, Hongyu Yang   +3 more
doaj   +1 more source

Why Questions on Time-Aware Spatial Keyword Queries in Traffic Networks

IEEE Access, 2022
Time-aware spatial keyword queries in traffic networks ( $TSKQT$ ) aim to retrieve top- $k$ result objects based on the ranking score considering spatial proximity, textual relevance, and temporal similarity simultaneously. However, due to inappropriate
Xiao Jia, Yanhong Li, Yihua Lan, Jinliang Huang, Xingang Zhang   +4 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Non-Rigid Cycle Consistent Bidirectional Network with Transformer for Unsupervised Deformable Functional Magnetic Resonance Imaging Registration

Brain Sciences
Background: In neuroscience research about functional magnetic resonance imaging (fMRI), accurate inter-subject image registration is the basis for effective statistical analysis. Traditional fMRI registration methods are usually based on high-resolution
Yingying Wang, Yu Feng, Weiming Zeng
doaj   +1 more source