Results 51 to 60 of about 2,160,125 (291)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Estimation of Minkowski tensors from digital grey-scale images
, 2014 It has been shown that local algorithms based on grey-scale images sometimes lead to asymptotically unbiased estimators for surface area and integrated mean curvature. This paper extends the results to estimators for Minkowski tensors.
Svane, Anne Marie
core +3 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Journal of Theoretical and Applied Electronic Commerce ResearchThe issue of image copyright infringement is prevalent in current e-commerce activities. Users employ methods such as image cropping, compression, and noise addition, making it difficult for traditional copyright detection technologies to identify and ...
Jikuan Xu, Jiamin Zhang, Junhan Wang
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Ensuring the discoverability of digital images for social work education : an online tagging survey to test controlled vocabularies [PDF]
, 2009 The digital age has transformed access to all kinds of educational content not only in text-based format but also digital images and other media. As learning technologists and librarians begin to organise these new media into digital collections for ...
Ballantyne, Neil, Daly, Ellen Katherine
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
PathologyGAN: Learning deep representations of cancer tissue [PDF]
, 2020 We apply Generative Adversarial Networks (GANs) to the domain of digital pathology. Current machine learning research for digital pathology focuses on diagnosis, but we suggest a different approach and advocate that generative models could drive forward ...
Murray-Smith, Roderick +2 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Indian Journal of Dental Research, 2014 Objective: This study aimed to compare digital techniques for evaluating dental enamel de-/remineralization. Materials and Methods: Sixty extracted molars were subjected to a process of de- and remineralization.
Patrícia Leite-Ribeiro +4 more
doaj +1 more source