Results 61 to 70 of about 671,039 (268)

Excavations at Cricklade, Wiltshire, 1975

open access: yesInternet Archaeology, 2003
The town of Cricklade in Wiltshire, England is one of the most regular examples of the class of Saxon urban fortresses, created as part of a fort-system in the late 9th century, which are included in the Burghal Hidage List.
Jeremy Haslam
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

For an autonomous existence of images: an archaeological perspective

open access: yesLumina, 2020
Monitoring and interpreting an increasing number of images has become part of people’s daily lives. These images trigger a complex process of relations that can result in direct human or non-human actions over people, over services or over the very space.
José Cláudio S. Castanheira
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

The application of photogrammetric numerical methods to the analysis of chromosome digital images

open access: yesGeodesy and Cartography, 2012
The article discusses research on identifying the possibilities and accuracy of chromosome digital images applying the theory of photogrammetric numerical methods and covariation functions.
Jonas Skeivalas   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

An MFF-SLIC Hybrid Superpixel Segmentation Method with Multi-Source RS Data for Rock Surface Extraction

open access: yesApplied Sciences, 2019
Multi-Source RS data integration is a crucial technology for rock surface extraction in geology. Both Terrestrial laser scanning (TLS) and Photogrammetry are primary non-contact active measurement techniques.
Xuefeng Yi   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Digital Tools for Working with New Testament Manuscripts

open access: yesOpen Theology, 2019
This article critically examines the functionalities and significance of three prominent digital tools that have become central to the study of Greek New Testament manuscripts.
Allen Garrick V.
doaj   +1 more source

Video-Based Abnormal Driving Behavior Detection via Deep Learning Fusions

open access: yesIEEE Access, 2019
Video-based abnormal driving behavior detection is becoming more and more popular for the time being, as it is highly important in ensuring safeties of drivers and passengers in the vehicle, and it is an essential step in realizing automatic driving at ...
Wei Huang   +5 more
doaj   +1 more source

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