Results 71 to 80 of about 2,078,615 (274)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Assessment of Reliability of Three Different Computer-Assisted Analysis Programs
Turkish Journal of Orthodontics, 2013 Objective:The aim of this study was to assess the reliability of cephalometric analysis using 3 different digital analysis programs.Methods:For this study, a dry human skull with the entire mandible, maxilla, and teeth was used.
Ebubekir Toy +3 more
doaj +1 more source
Adaptive Filters for 2-D and 3-D Digital Images Processing [PDF]
, 2012 Práce se zabývá adaptivními filtry pro vizualizaci obrazů s vysokým rozlišením. V teoretické části je popsán princip činnosti konfokálního mikroskopu a matematicky korektně zaveden pojem digitální obraz.
Martišek, Karel
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The application of photogrammetric numerical methods to the analysis of chromosome digital images
Geodesy and Cartography, 2012 The article discusses research on identifying the possibilities and accuracy of chromosome digital images applying the theory of photogrammetric numerical methods and covariation functions.
Jonas Skeivalas +2 more
doaj +1 more source
For an autonomous existence of images: an archaeological perspective
Lumina, 2020 Monitoring and interpreting an increasing number of images has become part of people’s daily lives. These images trigger a complex process of relations that can result in direct human or non-human actions over people, over services or over the very space.
José Cláudio S. Castanheira
doaj +1 more source
On Matching Skulls to Digital Face Images: A Preliminary Approach
, 2017 Forensic application of automatically matching skull with face images is an important research area linking biometrics with practical applications in forensics.
Jain, Arushi +5 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Applied Sciences, 2019 Multi-Source RS data integration is a crucial technology for rock surface extraction in geology. Both Terrestrial laser scanning (TLS) and Photogrammetry are primary non-contact active measurement techniques.
Xuefeng Yi +3 more
doaj +1 more source
Digital enhancement of flow field images [PDF]
Most photographs of experimentally generated fluid flow fields have inherently poor photographic quality, specifically low contrast. Thus, there is a need to establish a process for quickly and accurately enhancing these photographs to provide improved ...
Kudlinski, Robert A., Park, Stephen K.
core +1 more source