Results 41 to 50 of about 1,063 (216)

Traditional versus digital impression: compliance and preference in pediatric patients-review

open access: yesAnnali di Stomatologia, 2022
The purpose of this article is to compare the alginate impression with digital impression using the introral scanner Carestream 3600 and understand which is preferred by patients.
Valeria Luzzi   +7 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Digital Dentistry — Digital Impression and CAD/CAM System Applications

open access: yesJournal of Interdisciplinary Medicine, 2017
Digital imprint and computer-aided design/computer-aided manufacture (CAD/CAM) systems offer several benefits compared to traditional techniques. The use of a CAD/CAM system to scan preparations and generate restorations in-office, removes a second ...
Gabor Alin-Gabriel   +5 more
doaj   +1 more source

Effectiveness of creating digital twins with different digital dentition models and cone-beam computed tomography

open access: yesScientific Reports, 2023
Distortion of dentition may occur in cone-beam computed tomography (CBCT) scans due to artifacts, and further imaging is frequently required to produce digital twins. The use of a plaster model is common; however, it has certain drawbacks.
Joo-Hee Lee   +5 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Evaluation of digital and traditional impressions in orthodontics: a narrative review

open access: yesAnnali di Stomatologia
Objective: This narrative review explores the clinical, technical, and patient-centered differences between digital and traditional dental impression techniques, focusing on their role in orthodontics.
Sabina Saccomanno   +6 more
doaj   +1 more source

Comparison of digital and silicone impressions for single-tooth implants and two- and three-unit implants for a free-end edentulous saddle

open access: yesBMC Oral Health, 2021
Background The use of intraoral scanners (IOS) has facilitated the use of digital workflows for the fabrication of implant-supported prostheses not only for single missing teeth, but also for multiple missing teeth.
Koudai Nagata   +9 more
doaj   +1 more source

Accuracy of an intraoral digital impression: A review

open access: yesThe Journal of Indian Prosthodontic Society, 2019
Intraoral scanners (IOSs) are used for capturing the direct optical impressions in dentistry. The development of three-dimensional technology and the trend of increasing the use of IOSs in dental office routine lead to the need to assess the accuracy of intraoral digital impressions.
Aswani, Kanchan   +3 more
openaire   +3 more sources

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