Results 51 to 60 of about 35,413,485 (288)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Traditional versus digital impression: compliance and preference in pediatric patients-review

Annali di Stomatologia, 2022
The purpose of this article is to compare the alginate impression with digital impression using the introral scanner Carestream 3600 and understand which is preferred by patients.
Valeria Luzzi, Gabriele Di Carlo, Elvira Crupi, Ester Quarta, Francesca De Angelis, Stefano Di Carlo, Antonella Polimeni, Gaetano Ierardo   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Digital Dentistry — Digital Impression and CAD/CAM System Applications

Journal of Interdisciplinary Medicine, 2017
Digital imprint and computer-aided design/computer-aided manufacture (CAD/CAM) systems offer several benefits compared to traditional techniques. The use of a CAD/CAM system to scan preparations and generate restorations in-office, removes a second ...
Gabor Alin-Gabriel, Zaharia Cristian, Stan Adrian Tudor, Gavrilovici Andrei Mihai, Negruțiu Meda-Lavinia, Sinescu Cosmin   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Effectiveness of creating digital twins with different digital dentition models and cone-beam computed tomography

Scientific Reports, 2023
Distortion of dentition may occur in cone-beam computed tomography (CBCT) scans due to artifacts, and further imaging is frequently required to produce digital twins. The use of a plaster model is common; however, it has certain drawbacks.
Joo-Hee Lee, Hye-Lim Lee, In-Young Park, Sung-Woon On, Soo-Hwan Byun, Byoung-Eun Yang   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Evaluation of digital and traditional impressions in orthodontics: a narrative review

Annali di Stomatologia
Objective: This narrative review explores the clinical, technical, and patient-centered differences between digital and traditional dental impression techniques, focusing on their role in orthodontics.
Sabina Saccomanno, Lorenzo Ederli Silenzi, Mario Palermiti, Simone Ettore Salvati, Daniela Di Giandomenico, Eda Fani, Giuseppe Marzo   +6 more
doaj   +1 more source

Comparison of digital and silicone impressions for single-tooth implants and two- and three-unit implants for a free-end edentulous saddle

BMC Oral Health, 2021
Background The use of intraoral scanners (IOS) has facilitated the use of digital workflows for the fabrication of implant-supported prostheses not only for single missing teeth, but also for multiple missing teeth.
Koudai Nagata, Kei Fuchigami, Yurie Okuhama, Kana Wakamori, Hayato Tsuruoka, Toshifumi Nakashizu, Noriyuki Hoshi, Mihoko Atsumi, Katsuhiko Kimoto, Hiromasa Kawana   +9 more
doaj   +1 more source