Results 41 to 50 of about 8,762 (202)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Geoinformation assessment of digitalization in the urban space of Kaliningrad

Regional Studies, Regional Science, 2022
Cities around the globe that have residential areas spanning several eras of architecture face the challenge of developing a comfortable urban environment.
Anna Mikhaylova, Dmitry Hvaley, Andrey Mikhaylov   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Empower-Grief for Relatives of Cancer Patients: Implementation and Findings from an Exploratory Randomized Controlled Trial

Behavioral Sciences
Grief reactions among relatives of palliative care patients are often overlooked, with most interventions targeting Prolonged Grief Disorder (PGD) rather than its prevention. Few interventions have been developed for individuals at risk. This study aimed
David Dias Neto, Alexandra Coelho, Ana Nunes da Silva, Teresa Garcia Marques, Sara Albuquerque   +4 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Digital inclusion

, 2021
Diese Dissertation beschäftigt sich mit zwei gesellschaftlichen Verwerfungen: den Flüchtlingswellen in Deutschland und der COVID-19-Pandemie. Dabei konzentrieren wir uns auf den Einsatz von Informations- und Kommunikationstechnologie (IKT) als eines der wichtigsten Mittel, um diese Verwerfungen zu mildern/abzufangen und soziale Eingliederung zu fördern.
openaire   +3 more sources

Understanding Farmer preferences through citizen Science: Insights on potato varieties in Nigeria

Journal of Agriculture and Food Research
Conventional top-down potato breeding often overlooks farmer input, leading to varieties that may not be suited to local conditions, limiting their adoption and impact on smallholder farming.
K. Sharma, E. Atieno, J. Mugo, K. de Sousa, J. van Etten, S. Nyawade   +5 more
doaj   +1 more source

Diversity and Inclusion in Digital Education

, 2022
The idea for a dedicated Task Force on Diversity and Inclusion (TFD-I) emerged from the EADTU General Assembly meeting of October 2020 in which some member universities indicated to have this topic is a priority in their new strategies and policymaking.Diversity and Inclusion generate great attention and even more so for EADTU members as they have a ...
Aras Bozkurt, EADTU
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Adult Social Inclusion in a Digital Environment: Digital Social Inclusion

, 2021
ASIDE REPORT IV (March 2021 - July 2021) | [Agreement Number: 2019-1-PL01-KA204- 065689]
Nur Akarcay, Yeliz, Ochoa Siguencia, Luis, Sanchez Garcia, Javier, Ochoa-Daderska, Renata, Velinov, Emil, Niemczyk, Agata, Grodek-Szostak, Zofia   +6 more
openaire   +2 more sources