Results 61 to 70 of about 8,762 (202)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Analysis of Genotype‐by‐Environment Interaction, Farmers' Preferences, and Gender Response in Groundnut Breeding in Tanzania Using Triadic Comparison of Technologies

Food and Energy Security
High kernel yield and farmer‐ and market‐preferred traits are overriding considerations for groundnut (Arachis hypogaea L.) breeding, production and adoption.
Happy Daudi, Anthony Malehiwa Bujiku, Richard Oteng‐Frimpong, James Mwololo, Chris O. Ojiewo, Abhishek Rathore, Biswanath Das, Kauê deSousa, Mabel Nabateregga, Jacob vanEtten, Hussein Shimelis   +10 more
doaj   +1 more source

Barriers to digital inclusion in Africa: a systematic review

Educational Technology Quarterly
This study employed a systematic review to determine the barriers to digital inclusion in Africa. A total of 522 documents published between 2012 and 2024 were analysed.
Mohamed Salum Msoroka
doaj   +1 more source

Technological appropriation for the effective incorporation of open educational resources

Apertura, 2017
This article is based on a research which sought to identify the technological appropriation of five teachers who excel using technologies, according to their institute’s directors, to incorporate open educational resources (OER) to support educative ...
Fidel Ernesto Contreras Maradey, Marcela Georgina Gómez Zermeño   +1 more
doaj   +1 more source

Digital transformation and financial inclusion

SSRN Electronic Journal, 2020
The paper explores some of the main regulatory concerns and market barriers created by the digital transformation of the financial services industry and the implications for a more socially-inclusive financial system, particularly in developing and emerging market countries.
Karametaxas, Xenia Elisa, Alexander, Kern   +1 more
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Research Trends in Digital Financial Inclusion: A Bibliometric Analysis using VOSviewer

International Journal of Informatics, Information System and Computer Engineering
Digital financial inclusion (DFI) aims to provide affordable and sustainable financial services to financially excluded and underserved populations through cost-saving digital means.
Godwin Ahiase, Abdurrauf Umar, Abdulmalek Marwan. M. Saeed, Mohammad Abedin Rasuman, Epifania Rianti do Rego Tilman Suri   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Editorial: Knowledge graph technologies: the next Frontier of the food, agriculture, and water domains

Frontiers in Artificial Intelligence, 2023
Catherine Roussey, Christophe Guéret, Marie-Angélique Laporte   +2 more
doaj   +1 more source