Results 61 to 70 of about 553,132 (294)

Advancing Digital Inclusion in Low Income Australian Families: Interim Findings Report

open access: yes, 2022
Families living on low incomes are among the least digitally included Australians and are at greater risk of broader social exclusion than other Australians.
Mamalipurath, Jasbeer ; id_orcid   +13 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Empower-Grief for Relatives of Cancer Patients: Implementation and Findings from an Exploratory Randomized Controlled Trial

open access: yesBehavioral Sciences
Grief reactions among relatives of palliative care patients are often overlooked, with most interventions targeting Prolonged Grief Disorder (PGD) rather than its prevention. Few interventions have been developed for individuals at risk. This study aimed
David Dias Neto   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Digital Literacy Key Performance Indicators for Sustainable Development

open access: yesSocial Inclusion, 2020
The concept of digital literacy has been defined in numerous ways over the last two decades to incorporate rapid technological changes, its versatility, and to bridge the global digital divide.
Danica Radovanović   +8 more
doaj   +1 more source

Adult Social Inclusion in a Digital Environment: Digital Social Inclusion

open access: yes, 2021
ASIDE REPORT IV (March 2021 - July 2021) | [Agreement Number: 2019-1-PL01-KA204- 065689]
Nur Akarcay, Yeliz   +6 more
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Understanding Farmer preferences through citizen Science: Insights on potato varieties in Nigeria

open access: yesJournal of Agriculture and Food Research
Conventional top-down potato breeding often overlooks farmer input, leading to varieties that may not be suited to local conditions, limiting their adoption and impact on smallholder farming.
K. Sharma   +5 more
doaj   +1 more source

‘e-fatura’ - Estudo misto com participantes Seniores num projeto Municipal em Viseu

open access: yesPáginas a&b, 2020
The use of Information and Communication Technologies (ICT) is now democratized in the information society, however there are some age brackets that use less, such as senior citizens over the age of 65. Although the use of ICT among the senior population
Manuel Monteiro Barbosa   +1 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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