Results 71 to 80 of about 553,132 (294)
Technological appropriation for the effective incorporation of open educational resources
Apertura, 2017 This article is based on a research which sought to identify the technological appropriation of five teachers who excel using technologies, according to their institute’s directors, to incorporate open educational resources (OER) to support educative ...
Fidel Ernesto Contreras Maradey +1 more
doaj +1 more source
Does digital inclusion affect quality of life? Evidence from Australian household panel data
, 2020 The evidence on the role of information and communication technology (ICT) in enhancing quality of life (QoL) is mixed and the precise nature of this relationship is not yet fully understood. Existing single equation-based empirical works have provided a
Taylor, Brad +3 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Digital inclusion - the vision, the challenges and the way forward
, 2015 This paper considers the vision and aspiration of digital inclusion, and then examines the current reality. It looks beyond the rhetoric to provide an analysis of the status quo, a consideration of some facilitators and challenges to progress and some ...
Sandhu, J +4 more
core
Digital Financial Inclusion, Financial Efficiency and Green Innovation
, 2023 The financing difficulty of green innovation projects has always been an obstacle to enterprises’ green innovation. Digital financial inclusion provides a new opportunity to solve the financing difficulty of green innovation.
Yanru Li +3 more
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Enabling a Digital Birmingham: Our Journey Towards Digital Inclusion [PDF]
Discover the transformative impact of the Birmingham Digital Inclusion Strategy in our latest report. Learn how our collaborative efforts have empowered thousands with digital skills and access, contributing to a more inclusive, connected Birmingham ...
Kerrigan, Nathan
core +1 more source
Older adults’ digital inclusion: New challenges for Lithuanian social policy [PDF]
SHS Web of ConferencesLithuania, as most of the EU countries, has an aging population. At the beginning of 2019, there were 552.4 thousand elderly people (aged 65 and older), or 19.8 per cent of the total resident population.
Zemaitaityte Irena +3 more
doaj +1 more source