Results 81 to 90 of about 2,680,690 (272)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Research Trends in Digital Financial Inclusion: A Bibliometric Analysis using VOSviewer
International Journal of Informatics, Information System and Computer EngineeringDigital financial inclusion (DFI) aims to provide affordable and sustainable financial services to financially excluded and underserved populations through cost-saving digital means.
Godwin Ahiase +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Digital Inclusion for Students with Attention Deficit Hyperactivity Disorder [PDF]
, 2018 The Attention Deficit Hyperactivity Disorder is a syndrome characterized by distraction, impulsivity, forgetfulness and disorganization. The diagnosis requires considerable care and experience.
Mata, D. C. (Dayane) +2 more
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Digital Visual Skills Education for Digital Inclusion of Elder Women in the Community [PDF]
, 1915 This paper discusses the use of Digital Storytelling workshop practices for the basic digital visual skill education of elderly women. The DST workshop that was run by the authors provided the environment to experiment with the conventional DST workshop ...
Simsek, Burcu, Erdener, Burak
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2022 This publication has been funded with support from the European Commission. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.
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Information society policies 2.0: a critical analysis of the potential and pitfalls of social computing & informatics in the light of e-inclusion [PDF]
, 2010 In this paper we reflect on how research and policies can and/or should help in the development of a sustainable information society for all. More specifically, we critically investigate how social computing & informatics can entail both potential and ...
Verdegem, Pieter
core +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source