Results 31 to 40 of about 3,867,649 (355)

Digital Libraries and Crowdsourcing [PDF]

, 2018
Previously, libraries already outsourced some tasks. Now, however, they can also appeal to crowds of Internet users, with whom the libraries can have a more collaborative relationship than before. These Internet users may be volunteers or paid workers, and they could be working consciously, unconsciously or in the form of games.
openaire   +3 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Assessing the Components of Information Security in Accessing & Use of Digital Libraries

Iranian Journal of Information Processing & Management, 2021
Information security is one of the effective factors in protecting and using digital libraries which can help improve the status of these libraries.This research reviews the accessibility to information security of digital libraries in digital libraries ...
Fariborz Doroudi, Zeinab Jamshidi
doaj  

Digital libraries of the future – and the role of libraries

Library Hi Tech, 2006
PurposeThe purpose of this article is to introduce the digital libraries of the future, their enabling technologies and their organisational models.Design/methodology/approachThe paper first discusses the requirements for the digital libraries of the future, then presents the DILIGENT infrastructure as a technological response to these requirements and,
openaire   +5 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Duplicate Literature Detection for Cross-Library Search

Cybernetics and Information Technologies, 2016
The proliferation of online digital libraries offers users a great opportunity to search their desired literatures on Web. Cross-library search applications can help users search more literature information from multiple digital libraries.
Liu Wei, Zeng Jianxun
doaj   +1 more source

Creating Digital Identity for Arabic National Libraries from Content Analysis of Missions & Vision Statements Using Machine Learning Algorithms. [PDF]

المجلة المصرية لعلوم المعلومات
Creating Digital Identity for Arabic National Libraries from Content Analysis of Missions & Vision Statements Using Machine Learning Algorithms.This study explores the utilization of ML content analysis algorithms to create a robust digital identity for ...
مؤمن سيد النشرتي النشرتيي
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Perceptions of usability and usefulness of digital libraries

Int. J. Humanit. Arts Comput., 2012
This paper provides an overview of a case study research that investigated the use of Digital Library (DL) resources in two undergraduate classes and explored faculty and students' perceptions of educational digital libraries.
Krystyna K. Matusiak
semanticscholar   +1 more source