Results 51 to 60 of about 584,239 (266)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

DEVELOPMENT OF METHODOLOGY FOR DIGITAL MANAGEMENT BY SOCIO-ECONOMIC ORGANIZATIONS

Вестник университета, 2018
The approaches, principles, designs serve as methodological basis of scientific research, professional activity and managerial education. Its application in the modern socioeconomic organization increasingly takes into account the possibilities of ...
A. Raychenko
doaj   +1 more source

Digital medication management in polypharmacy

Deutsches Ärzteblatt international
BACKGROUND: Inappropriate drug prescriptions for patients with polypharmacy can have avoidable adverse consequences. We studied the effects of a clinical decision-support system (CDSS) for medication management on hospitalizations and mortality. METHODS: This stepped-wedge, cluster-randomized, controlled trial involved an open cohort of adult patients ...
Bruenn, Robin, Basten, Jale, Lemke, Dorothea, Piotrowski, Alexandra, Soeling, Sara, Surmann, Bastian, Greiner, Wolfgang, Grandt, Daniel, Kellermann-Muehlhoff, Petra, Harder, Sebastian, Glasziou, Paul, Perera, Rafael, Koeberlein-Neu, Juliane, Ihle, Peter, van den Akker, Marjan, Timmesfeld, Nina, Muth, Christiane   +16 more
openaire   +2 more sources

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Data management in digital management

Vestnik of Astrakhan State Technical University. Series: Economics
The article examines a promising direction of digital development of management systems – data management, focused on ensuring high efficiency of business functioning in the context of extensive digital transformation of socio-economic systems. The importance of improving business management systems through the development of data management strategies
Elena Nikolaevna Sheremetyeva, Anna Kirillovna Adgizalova, Yuri Gennadievich Popov   +2 more
openaire   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Digital Management Methodology for Building Production Optimization through Digital Twin and Artificial Intelligence Integration

Buildings
In a construction project schedule, delays in delivery are one of the most important problems. Delays can be caused by several project components; however, the issue is amplified when delays occur simultaneously.
Giuseppe Piras, Francesco Muzi, Virginia Adele Tiburcio   +2 more
doaj   +1 more source

DIGITALIZATION OR DIGITAL ECONOMY: PROBLEMS AND PERSPECTIVES

Вестник университета, 2019
The so-called «digitalization» not only as a management tool in economy (digital economy), but also as a historical phenomenon in the evolution of a society and all social life of a human being has been considered.
L. Ivanovskaya
doaj   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Artificial Intelligence as the Engine of Modern Management: From Decision-Making Efficiency to Organizational Performance [PDF]

Ovidius University Annals: Economic Sciences Series
Rapid advances in artificial intelligence (AI) are significantly changing management practices and the ways in which organizations achieve their performance goals in the era of digitalization. This research examines the connection between the use of AI
Petruta Ionela Stanca
doaj