Conquering the Tyranny of Number With Digital Microfluidics [PDF]
Frontiers in Chemistry, 2021 The development of large-scale integration based on soft lithography has ushered a new revolution in microfluidics. This technology, however, relies inherently on pneumatic control of micromechanical valves that require air pressure to operate, while ...
Ya-Tang Yang, Tsung-Yi Ho
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Characterization of Inkjet-Printed Digital Microfluidics Devices [PDF]
Sensors, 2021 Digital microfluidics (DMF) devices enable precise manipulation of small liquid volumes in point-of-care testing. A printed circuit board (PCB) substrate is commonly utilized to build DMF devices.
Shiyu Chen +3 more
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All-in-One Digital Microfluidics System for Molecular Diagnosis with Loop-Mediated Isothermal Amplification [PDF]
Biosensors, 2022 In this study, an “all-in-one” digital microfluidics (DMF) system was developed for automatic and rapid molecular diagnosis and integrated with magnetic bead-based nucleic acid extraction, loop-mediated isothermal amplification (LAMP), and real-time ...
Siyi Hu +8 more
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Digital Microfluidics for Nucleic Acid Amplification [PDF]
Sensors, 2017 Digital Microfluidics (DMF) has emerged as a disruptive methodology for the control and manipulation of low volume droplets. In DMF, each droplet acts as a single reactor, which allows for extensive multiparallelization of biological and chemical ...
Beatriz Coelho +6 more
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Digital Microfluidics for Single Bacteria Capture and Selective Retrieval Using Optical Tweezers [PDF]
Micromachines, 2020 When screening microbial populations or consortia for interesting cells, their selective retrieval for further study can be of great interest. To this end, traditional fluorescence activated cell sorting (FACS) and optical tweezers (OT) enabled methods ...
Phalguni Tewari Kumar +8 more
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Digital Microfluidics: A New Paradigm for Radiochemistry [PDF]
Molecular Imaging, 2015 The emerging technology of digital microfluidics is opening up the possibility of performing radiochemistry at the microliter scale to produce tracers for positron emission tomography (PET) labeled with fluorine-18 or other isotopes.
Pei Yuin Keng, R. Michael van Dam
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Digital Manufacturing for Microfluidics
Annual Review of Biomedical Engineering, 2019 The microfluidics field is at a critical crossroads. The vast majority of microfluidic devices are presently manufactured using micromolding processes that work very well for a reduced set of biocompatible materials, but the time, cost, and design constraints of micromolding hinder the commercialization of many devices.
Albert Folch, Nirveek Bhattacharjee
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A Novel and Robust Single-cell Trapping Method on Digital Microfluidics [PDF]
Bio-Protocol, 2020 Due to cell heterogeneity, the differences among individual cells are averaged out in bulk analysis methods, especially in the analysis of primary tumor biopsy samples from patients.
Jiao Zhai +8 more
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Active-matrix digital microfluidics design for field programmable high-throughput digitalized liquid handling [PDF]
iScienceSummary: Digital liquid sample handling is an enabling tool for cutting-edge life-sciences research. We present here an active-matrix thin-film transistor (TFT) based digital microfluidics system, referred to as Field Programmable Droplet Array (FPDA ...
Dongping Wang +11 more
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Digital Microfluidics in Newborn Screening for Mucopolysaccharidoses: A Progress Report [PDF]
International Journal of Neonatal Screening, 2020 Newborn screening (NBS) for mucopolysaccharidosis type I (MPS I, Hurler syndrome) is currently conducted in about two-fifths of the NBS programs in the United States and in a few other countries. Screening is performed by measurement of residual activity
Jon Washburn, David S. Millington
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