Results 41 to 50 of about 13,966 (250)

Digital microfluidic immunocytochemistry in single cells [PDF]

open access: yesNature Communications, 2015
AbstractWe report a new technique called Digital microfluidic Immunocytochemistry in Single Cells (DISC). DISC automates protocols for cell culture, stimulation and immunocytochemistry, enabling the interrogation of protein phosphorylation on pulsing with stimulus for as little as 3 s.
Ng, Alphonsus H. C.   +4 more
openaire   +2 more sources

Circulating tumour cell RNA characterisation from colorectal cancer patient blood after inertial microfluidic enrichment

open access: yesMethodsX, 2019
The detection and molecular analysis of circulating tumour cells (CTCs) potentially provides a significant insight to the characterisation of disease, stage of progression and therapeutic options for cancer patients.
Marnie Winter   +8 more
doaj   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

open access: yesAdvanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett   +19 more
wiley   +1 more source

A digital microfluidic biochip synthesis framework

open access: yes2012 IEEE/IFIP 20th International Conference on VLSI and System-on-Chip (VLSI-SoC), 2012
Synthesis of digital microfluidic biochips (DMFBs) is a crucial to the advancement and realization of miniaturized, automated, programmable biochemistry solutions; synthesis is performed in three steps: scheduling, placement and routing. In principle, algorithms for specific steps should be interchangeable with one another; however, different research ...
Daniel T. Grissom   +6 more
openaire   +3 more sources

Digital Microfluidics with Bubble Manipulations by Dielectrophoresis

open access: yesInternational Journal of Automation and Smart Technology, 2012
This paper presents basic bubble manipulations, including transporting, splitting, and merging, by dielectrophoresis (DEP) in an oil environment. In our presented method, bubbles are placed between parallel plates in an oil medium of a low vapor pressure,
Shih-Kang Fan, Di-Yu Lin
doaj   +1 more source

Transfer Printing and Reconfiguration of Soft Electronics Using Digital Microfluidics and Laser Machining

open access: yesAdvanced Functional Materials, EarlyView.
This paper presents a digital microfluidics‐based technique for transferring and reconfiguring soft nanomembranes. Laser‐machined nanothin membranes are picked up, transported, and aligned via tailored surface tension and the actuation of water droplets, enabling the development of flexible electronics, the integration of functional materials on 3D ...
Quang Anh Nguyen   +15 more
wiley   +1 more source

Influence of Inclined Chip Angles on Dynamic Contact Angle Variations in Digital Microfluidics [PDF]

open access: yesMATEC Web of Conferences
The impact of tilted angles on contact angles of water droplets in digital microfluidics was investigated. Experiments were conducted tilting the chip from 0 to 10 degrees at voltage increments of 50V from 250V to 400V DC.
Ali Moazzam   +5 more
doaj   +1 more source

Digital Microfluidic Platform to Maximize Diagnostic Tests with Low Sample Volumes from Newborns and Pediatric Patients

open access: yesDiagnostics, 2020
“Children are not tiny adults” is an adage commonly used in pediatrics to emphasize the fact that children often have different physiological responses to sickness and trauma compared to adults.
Rama S. Sista   +14 more
doaj   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera   +6 more
wiley   +1 more source

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