Results 41 to 50 of about 2,871,670 (306)

Advances in Testing Techniques for Digital Microfluidic Biochips

open access: yesSensors, 2017
With the advancement of digital microfluidics technology, applications such as on-chip DNA analysis, point of care diagnosis and automated drug discovery are common nowadays.
Vineeta Shukla   +3 more
doaj   +1 more source

Recent advancements in single-cell metabolic analysis for pharmacological research

open access: yesJournal of Pharmaceutical Analysis, 2023
Cellular heterogeneity is crucial for understanding tissue biology and disease pathophysiology. Pharmacological research is being advanced by single-cell metabolic analysis, which offers a technique to identify variations in RNA, proteins, metabolites ...
Ying Hou, Hongren Yao, Jin-Ming Lin
doaj   +1 more source

An efficient protocol to use feedback-controlling digital microfluidic fluorimetric sensor for detection of mercury (II) in coastal seawaters

open access: yesMethodsX, 2019
Mercury ion is a highly toxic anthropogenic pollutants and has serious well-known effects on human. There is an ever-growing demand for convenient detection of mercury driven contaminants in environment, including coastal seawater.
Shuang Han   +4 more
doaj   +1 more source

Dynamic Contact Angle Variation with Applied Voltage and Droplet Volume in Digital Microfluidics

open access: yesEngineering Proceedings, 2023
Digital microfluidics allows for controlled droplet movement by applying AC or DC voltages. In this research, we investigated the dynamic contact angle variation of droplets at different voltages and droplet volumes in a digital microfluidics platform ...
Moazzam Ali   +5 more
doaj   +1 more source

An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing. [PDF]

open access: yes, 2018
Sequencing technologies have undergone a paradigm shift from bulk to single-cell resolution in response to an evolving understanding of the role of cellular heterogeneity in biological systems.
Abate, Adam R   +3 more
core   +2 more sources

Optical imaging techniques in microfluidics and their applications [PDF]

open access: yes, 2012
Microfluidic devices have undergone rapid development in recent years and provide a lab-on-a-chip solution for many biomedical and chemical applications.
Lee, Lap Man, Wu, Jigang, Zheng, Guoan
core   +1 more source

Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance in an isogenic bacterial population [PDF]

open access: yes, 2020
Since antibiotic resistance is a major threat to global health, recent observations that the traditional test of minimum inhibitory concentration (MIC) is not informative enough to guide effective antibiotic treatment are alarming.
Debski, Pawel R.   +9 more
core   +1 more source

Characterization of a Droplet Containing the Clustered Magnetic Beads Manipulation by Magnetically Actuated Chips

open access: yesMicromachines, 2022
A magnetically actuated chip was successfully developed in this study to perform the purpose of transportation for a droplet containing clustered magnetic beads.
Sheng-Huang Yen   +3 more
doaj   +1 more source

Amorphous silicon photosensors integrated in microfluidic structures as a technological demonstrator of a “true” Lab-on-Chip system

open access: yesSensing and Bio-Sensing Research, 2015
In this paper we present a compact technological demonstrator including on the same glass substrate an electrowetting-on-dielectrics (EWOD) system, a linear array of amorphous silicon photosensor and a capillary-driven microfluidic channel.
Domenico Caputo   +5 more
doaj   +1 more source

Newborn Screening for Fabry Disease: Current Status of Knowledge

open access: yesInternational Journal of Neonatal Screening, 2023
Fabry disease is an X-linked progressive lysosomal disorder, due to α-galactosidase A deficiency. Patients with a classic phenotype usually present in childhood as a multisystemic disease.
Vincenza Gragnaniello   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy