Results 61 to 70 of about 166,599 (278)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Biodiversity informatics: the challenge of linking data and the role of shared identifiers [PDF]
, 2008 A major challenge facing biodiversity informatics is integrating data stored in widely distributed databases. Initial efforts have relied on taxonomic names as the shared identifier linking records in different databases.
Altschul +11 more
core +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Scenarios and research issues for a network of information [PDF]
, 2008 This paper describes ideas and items of work within the framework of the EU-funded 4WARD project. We present scenarios where the current host-centric approach to infor- mation storage and retrieval is ill-suited for and explain how a new networking ...
Dannewitz, Christian +5 more
core +4 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Digital Identifier Systems: Comparative Evaluation
Iranian Journal of Information Processing & Management, 2015 Identifier is one of the main elements in identifying an object in digital environment. Digital identifier systems were developed followed by a lot of problems such as violation of persistency and uniqueness of physical identifiers and URL in digital ...
Hamid Reza Khedmatgozar +2 more
doaj
Demetra, 2013 Mais uma vez, trazemos importantes novidades editoriais: a atribuição de DOI (Digital Object Identifier) aos textos, a publicação do primeiro suplemento temático, a inauguração da Seção de Debates, a reafirmação do crescimento no número de artigos por ...
Shirley Donizete Prado
doaj +1 more source
Using object-oriented databases in face recognition
Системный анализ и прикладная информатика, 2020 The aim of the work is to develop an algorithm functioning by a face recognition system using object-oriented databases. The system provides automatic identification of the desired object or identifies someone using a digital photo or video frame from a ...
X. C. Dong, V. I. Ionin
doaj +1 more source
Ocean data publication cookbook [PDF]
, 2013 This cookbook is an outcome of the 5th session of the SCOR/IODE/MBLWHOI Library Workshop on Data Publication and is posted here by permission of UNESCO.Executive summary: This “Cookbook” has been written for data managers and librarians who are ...
Chandler, Cynthia L. +5 more
core