Results 81 to 90 of about 166,599 (278)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Self-consistent Modeling of the $I_c$ of HTS Devices: How Accurate do Models Really Need to Be?

open access: yes, 2014
Numerical models for computing the effective critical current of devices made of HTS tapes require the knowledge of the Jc(B,theta) dependence, i.e. of the way the critical current density Jc depends on the magnetic flux density B and its orientation ...
Grilli, Francesco   +3 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Evolution of NASA's Earth Science Digital Object Identifier Registration System [PDF]

open access: yes
NASA's Earth Science Data and Information System (ESDIS) Project has implemented a fully automated system for assigning Digital Object Identifiers (DOIs) to Earth Science data products being managed by its network of 12 distributed active archive centers
James, Nathan, Wanchoo, Lalit
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Generating Metadata on a Shoestring sans Programmer, with Our Good Friend, Excel (or Any Spreadsheet)

open access: yesCode4Lib Journal, 2008
How to use Excel to generate metadata for any encoded filename or identifier for any digital object whose attributes can be expressed in an abbreviated form.
Jill Strass
doaj  

Developing Data Citations from Digital Object Identifier Metadata [PDF]

open access: yes
NASA's Earth Science Data and Information System (ESDIS) Project has been processing information for the registration of Digital Object Identifiers (DOI) for the last five years of which an automated system has been in operation for the last two years ...
James, Nathan, Wanchoo, Lalit
core   +1 more source

PURR - The Persistent URL Resource Resolver [PDF]

open access: yes, 2001
URLs have a precarious functional lifespan. They resolve the intended target (web page, PDF, audio stream, and so on) only so long as the target is available, otherwise they'll point to a dead end.
Sponsler, Ed
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

REVISTA COMPLETA (V.8, N.1) Dossiê: O Mundo Antigo: Literatura e Historiografia

open access: yese-Hum: Revista das Áreas de Humanidade do Centro Universitário de Belo Horizonte, 2015
eoi/doi Deposit-Electronic Object Identifier http://eoi.citefactor.org/10.11248/ehum.v8i1.1678 O Conteúdo completo da Revista e de seus autores organizado em livro  Códice digital.
Rangel Cerceau Netto
doaj  

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