Results 31 to 40 of about 35,393,546 (271)

Pengaruh Edukasi Digital Parenting Terhadap Pengetahuan Orang Tua Tentang Penggunan Gatget Pada Anak Usia Sekolah

open access: yesJurnal Keperawatan 'Aisyiyah
Penggunaan gadget pada anak usia sekolah yang tidak terkontrol dapat berdampak negatif pada perkembangan anak, salah satunya disebabkan oleh kurangnya pengetahuan orang tua tentang digital parenting.
nana erika chandra   +2 more
doaj   +1 more source

Autonomy vs. control: Associations among parental mediation, perceived parenting styles, and U. S. adolescents’ risky online experiences

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace, 2022
Parenting that supports autonomy and promotes open communication leads to better outcomes for adolescents. In an era of digital media, however, adolescent desire for autonomy may conflict with parental mediation practices that exert control over media ...
Rachel Young, Melissa Tully
doaj   +1 more source

Evaluation of the national roll-out of parenting programmes across England : the parenting early intervention programme (PEIP) [PDF]

open access: yes, 2013
Background: Evidence based parenting programmes can improve parenting skills and the behaviour of children exhibiting, or at risk of developing, antisocial behaviour.
Lindsay, G   +5 more
core   +2 more sources

Digital divide begins at home: Socioeconomic disparities in digital parenting practices in rural China

open access: yesActa Psychologica
The rapid expansion of digital technologies has transformed children's lives, presenting new challenges for caregivers navigating the digital landscape.
Jiayi Shi, Ling Li, Hui Li, Dandan Wu
doaj   +1 more source

Parenting Styles And Their Impact On Online Gaming Addiction: Mediating Role Of Psychological Well-Being In Indonesia [PDF]

open access: yesSHS Web of Conferences
In Indonesia’s distinctive cultural and digital milieu, this study explores the interconnectedness between parenting styles, psychological well-being, and online game addiction in individuals aged 15-30.
Achmad Rendy Alfiannoor   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Sharenting, digital parenting processes, and children’s problematic internet use: A cross-sectional study

open access: yesJournal of Social Media Research
The rapid integration of digital technologies into family life has transformed parenting practices, particularly through the widespread phenomenon of sharenting. While sharenting has primarily been examined as a matter of privacy and digital ethics, its
Berke Taşçı, Bedia Sultan Önal
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

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