Results 41 to 50 of about 35,393,546 (271)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Parenting on a digital leash: time pressure, parenting guilt, and emotional exhaustion in Chinese dual-earner families

Frontiers in Psychology
BackgroundDigital tools are increasingly integrated into parenting, but their psychological costs remain unclear. This study investigates whether digitally-mediated parenting intensity predicts emotional exhaustion among Chinese dual-earner parents, and ...
Zhongya Ji, Yao Lu, Guanxin Yao
doaj   +1 more source

‘Putting all my eggs into the app’: Self, relational and systemic surveillance of mothers’ use of digital technologies during the transition to parenting

Digital Health, 2023
This paper builds on thematic findings from a larger study that explored how digital technologies (e.g. smartphones, apps, search engines) shape expectant and new mothers’ early parenting practices.
Jodi Hall, Bradley Hiebert, Danica Facca, Lorie Donelle   +3 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

A comparison of the effectiveness of three parenting programmes in improving parenting skills, parent mental-well being and children's behaviour when implemented on a large scale in community settings in 18 English local authorities : the parenting early intervention pathfinder (PEIP) [PDF]

, 2011
Background There is growing evidence that parenting programmes can improve parenting skills and thereby the behaviour of children exhibiting or at risk of developing antisocial behaviour.
Lindsay Geoff, Strand Steve, Davis, Hilton, Lindsay, Geoff, Davis Hilton, Strand, Steve   +5 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Exploring the influence of digital parental awareness on digital play addiction among preschoolers

Frontiers in Psychology
BackgroundThe widespread use of digital devices has made digital play an important part of children’s daily lives. While digital play provides entertainment and engagement, excessive use may lead to addiction-like behaviors, prompting concerns among ...
Yüksel B. Yüksel Aykanat, Büşra Somuncu Çoksağır, Alanoud A. Albatli, Selahattin Semiz, Juan Gómez-Salgado, Juan Gómez-Salgado, Murat Yıldırım, Murat Yıldırım   +7 more
doaj   +1 more source

Dijital Ebeveynlerin Sosyal Medyada Mahremiyet Algısı

Online Academic Journal of Information Technology, 2019
İletişim teknolojileri, 21.yy. başlarında kazandığı ivmeyle bireyin iletişim alışkanlıklarında köklü değişimler meydana getirmektedir. İnternet erişim olanaklarının artması ve mobil iletişim teknolojilerinin yaygınlaşmasıyla birlikte ortaya çıkan ...
Mustafa Bostancı
doaj   +1 more source

Minimal Important Change and Minimal Clinically Important Difference in Pain and Function With Exercise in Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to estimate the minimal important change (MIC) and minimal clinically important difference (MCID) for pain and physical function in individuals with hip osteoarthritis (OA) following a physiotherapist‐guided exercise intervention.
Yareni Guerrero, Fiona Dobson, Venkatesha Venkatesha, Kim Allison, Gabrielle Knox, Libby Spiers, Travis Haber, David J Hunter, Michelle Hall   +8 more
wiley   +1 more source