Results 231 to 240 of about 540,702 (278)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Modernizing Colorectal Cancer Care With Artificial Intelligence: Real-Time Detection, Radiomics, and Digital Pathology. [PDF]

Cureus
Nasr E, Al-Hamid Z, Younan MH, Omran M, Sarsam M, Abdellatif M.   +5 more
europepmc   +1 more source

Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models

Advanced Science, EarlyView.
Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler, Tim Lange, Sophia‐Marie Bach, Soeren S. Lienkamp, Nicole Endlich   +4 more
wiley   +1 more source

The Relationship Between Non-Invasive Tests and Digital Pathology for Quantifying Liver Fibrosis in MASLD. [PDF]

Diagnostics (Basel)
Wei X, Qiu L, Wang X, Shao C, Zhao J, Yang Q, Chen J, Yin M, Ehman RL, Zhang J.   +9 more
europepmc   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

Enhancing early prediction of pathological complete response in breast cancer using attention-based convolutional neural networks in digital pathology. [PDF]

Digit Health
Comes MC, Lupo A, Bozzi A, Fanizzi A, Cirillo A, Nunzio G, Pastena MI, Rizzo A, Guven DC, Vitale E, Zito FA, Bove S, Massafra R.   +12 more
europepmc   +1 more source

Pathologists' user experience in the era of digital pathology: a KAP study in a region of emerging digitization. [PDF]

Front Digit Health
Sughayer MA, Souan L, Tadros JS.
europepmc   +1 more source

Digital Pathology Quantification of the Continuum of Cirrhosis Severity in Human Liver Biopsies. [PDF]

Liver Int
Petitjean L, Chen L, Zhang X, Schiano T, Petitjean M, Sanyal AJ, Fiel M.   +6 more
europepmc   +1 more source

DuXplore: A Dual-Hierarchical Deep Learning Model for Prognostic Prediction of Hepatocellular Carcinoma in Digital Pathology. [PDF]

Diagnostics (Basel)
Zhang H, Liu M, Zhao X, Zhang Y, Sui L.
europepmc   +1 more source