Results 61 to 70 of about 950,229 (283)
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
A Comparative Analysis for Harnessing Digital Twin Platforms for Net-Zero Manufacturing
IEEE AccessA comprehensive review of digital twin platforms carried out through comparative study and analysis of nearly (~100+aprox) digital twins. It includes commercial and open-source digital twin platforms, with a primary aim of making informed decisions for ...
Dattatraya Parle +5 more
doaj +1 more source
Open-source digital technologies for low-cost monitoring of historical constructions [PDF]
, 2017 This paper shows new possibilities of using novel, open-source, low-cost platforms for the structural health monitoring of heritage structures. The objective of the study is to present an assessment of increasingly available open-source digital modeling ...
Basto, Camilo +2 more
core +2 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
User Participation in Value Creation [PDF]
, 2018 This article examines HM Treasury’s proposal to account for the active participation of users in value creation in certain digital platforms. The first key question is whether there is any reason to believe, as HM Treasury suggests, that users only ...
Grinberg, Itai
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein +7 more
wiley +1 more source
Introduction – Digital Platforms and Agency
LateralThis piece introduces a special section on digital platforms and agency. It unpacks the tension between, on the one hand, the imposition of digital platforms upon cultures by immensely-powerful technology companies, and on the other hand, the emergence ...
Reed Van Schenck, Elaine Venter
doaj +1 more source
The rise of social ereading : interactive ebook platforms and the development of online reading communities : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in English at Massey University, Manawatū, New Zealand [PDF]
, 2016 Ebooks have caused a revolution in how people read fiction. Ereading devices and apps now integrate interactive features which have led to the development of digital reading communities populated by millions of readers from around the world, with a ...
Pawley, Jessica Leigh
core
Data Collection for Mental Health Studies Through Digital Platforms : Requirements and Design of a Prototype [PDF]
, 2017 Background: Mental and behavioral disorders are the main cause of disability worldwide. However, their diagnosis is challenging due to a lack of reliable biomarkers; current detection is based on structured clinical interviews which can be biased by the ...
Alakörkkö, Tuomas +6 more
core +1 more source