Results 91 to 100 of about 37,825,652 (272)

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno   +19 more
wiley   +1 more source

Digital preservation: concepts and methods

open access: yesKnjižnica, 2010
The paper is a review of digital preservation theory and practice. Main concepts, standards and recommendations in this field as well methods implemented by digital archives (libraries and archival institutions responsible for digital preservation) are ...
Alenka Kavčič-Čolić
doaj   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab   +19 more
wiley   +1 more source

Case study: the University of Glasgow’s digital preservation journey 2017-2019

open access: yesInsights: The UKSG Journal, 2019
This case study documents the University of Glasgow’s digital preservation journey during 2017 and 2018. The University recognized that action was required to ensure the long-term preservation of key corporate records and archival material.
Alison Spence   +2 more
doaj   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

A Problem of Long - Term Digital Preservation: Difference in Humanities and Natural Sciences

open access: yesBibliotheca Lituana, 2014
The article deals with the requirements and needs for long-term digital preservation in different areas of scholarly work. The concept of long-term digital preservation is introduced by comparing it to digitization and archiving concepts and defined with
Elena Macevičiūtė
doaj   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram   +3 more
wiley   +1 more source

Introdução à preservação digital : conceitos, estratégias e actuais consensos [PDF]

open access: yes, 2006
This book aims at describing and contextualizing the main activities carried out internationally in the past 10 years in the field of digital preservation.
Ferreira, Miguel
core   +1 more source

VERS: Practical Digital Preservation [PDF]

open access: yesDocument numérique, 2004
La strategie d’archivage electronique de Victoria, plus connue sous le nom de VERS, est une methode pragmatique pour la conservation a long terme des documents electroniques. Depuis son demarrage en 1995 jusqu’a aujourd’hui, le programme VERS a beneficie d’une collaboration efficace entre le gouvernement de l’Etat de Victoria, le monde industriel et le
openaire   +2 more sources

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli   +13 more
wiley   +1 more source

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