Results 71 to 80 of about 269,061 (300)

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Beyond OAIS : towards a reliable and consistent digital preservation implementation framework [PDF]

open access: yes, 2009
Current work in digital preservation (DP) is dominated by the "Open Archival Information System" (OAIS) reference framework specified by the international standard ISO 14721:2003.
Milena Dobreva   +5 more
core   +1 more source

HathiTrust and Local Digital Stewardship: A Case Study in How Massive Digital Libraries Affect Local Digital Resources Decisions

open access: yesInternational Journal of Librarianship, 2017
This article reviews the influence that massive digital libraries like the HathiTrust Digital Library can have on local, smaller institutions’ digitization, preservation, and curation programs.
Heidi M. Winkler, Joy M. Perrin
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Software archives as a vital base for digital preservation strategies [PDF]

open access: yes, 2010
Software archives are vital parts in long-term preservation strategies of digital artifacts because almost every digital preservation strategy depends on additional software components. At this point a software archive becomes important.
van den Dobbelsteen, Maurice   +2 more
core  

Attrition Defenses for a Peer-to-Peer Digital Preservation System [PDF]

open access: yes, 2004
In peer-to-peer systems, attrition attacks include both traditional, network-level denial of service attacks as well as application-level attacks in which malign peers conspire to waste loyal peers' resources.
David S. H. Rosenthal   +10 more
core   +1 more source

Digital Preservation

open access: yesD-Lib Magazine, 2005
Developing preservation processes for a trusted digital repository will require the integration of new methods, policies, standards, and technologies. Digital repositories should be able to preserve electronic materials for periods at least comparable to existing preservation methods. Modern computing technology in general is barely fifty years old and
Ronald Jantz, Michael J. Giarlo
openaire   +2 more sources

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

ERPANET OAIS Training Report [PDF]

open access: yes, 2003
The training seminar provided accessible and transferable training to participants on the OAIS model itself, its functionalities, and its wider potential applications. Participants gained familiarity with the main features of the model, and examined some

core  

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

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