Results 71 to 80 of about 262,813 (297)
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
A model for digital preservation repository risk relationships [PDF]
, 2012 The paper introduces the Preserved Object and Repository Risk Ontology (PORRO), a model that relates preservation functionality with associated risks and opportunities for their mitigation.
McHugh, A.
core
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Technology responsiveness for digital preservation: a model
, 2009 Digital preservation may be defined as the cumulative actions undertaken by an organisation or individual to ensure that digital content is usable across generations of information technology.
McGovern, N.Y.
core
LIFE3: A predictive costing tool for digital collections [PDF]
, 2010 Predicting the costs of long-term digital preservation is a crucial yet complex task for even the largest repositories and institutions. For smaller projects and individual researchers faced with preservation requirements, the problem is even more ...
McCann, Patrick +7 more
core
A Problem of Long - Term Digital Preservation: Difference in Humanities and Natural Sciences
Bibliotheca Lituana, 2014 The article deals with the requirements and needs for long-term digital preservation in different areas of scholarly work. The concept of long-term digital preservation is introduced by comparing it to digitization and archiving concepts and defined with
Elena Macevičiūtė
doaj +1 more source
Introduction to Digital Preservation
, 2017 Introduction to digital preservation for PASIG 2017 Oxford Bootcamp Day on 11 September 2017.
openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Case study: the University of Glasgow’s digital preservation journey 2017-2019
Insights: The UKSG Journal, 2019 This case study documents the University of Glasgow’s digital preservation journey during 2017 and 2018. The University recognized that action was required to ensure the long-term preservation of key corporate records and archival material.
Alison Spence +2 more
doaj +1 more source