Results 51 to 60 of about 35,818,510 (271)

LIFE3: A predictive costing tool for digital collections [PDF]

, 2010
Predicting the costs of long-term digital preservation is a crucial yet complex task for even the largest repositories and institutions. For smaller projects and individual researchers faced with preservation requirements, the problem is even more ...
Wheatley, P., McCann, P., Hole, B., Lin, L.   +3 more
core   +5 more sources

Evolving Digital Preservation Appraisal Criteria and Selection

Preservation, Digital Technology & Culture
This paper expands the 2018 article “Approaching Appraisal: Framing Criteria for Selecting Digital Content for Preservation” with an examination, review, and discussion.
Tallman Nathan, Work Lauren, Anderson Martha, Denault Chelsea, Dressler Virginia   +4 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

QEMU - A Crucial Building Block in Digital Preservation Strategies [PDF]

, 2011
Emulation as long-term preservation strategy depends on usable, reliable and sustainable emulators to preserve old or obsolete original digital environments.
Rechert, Klaus, Tchayep, Achille Nana, Suchodoletz, Dirk von   +2 more
core   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Política arquivística de preservação digital: um estudo sobre sua aplicabilidade em instituições públicas federais

Perspectivas em Ciência da Informação
Resumo O presente artigo apresenta parte dos resultados obtidos em uma pesquisa de mestrado sobre a preservação do patrimônio documental arquivístico da Federação Espírita do Grande do Sul (FERGS), desenvolvida no Programa de Pós-Graduação Profissional ...
William Silva, Daniel Flores
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Challenges and opportunities in the evolving digital preservation landscape: reflections from Portico

Insights: The UKSG Journal, 2018
There has been tremendous growth in the amount of digital content created by libraries, publishers, cultural institutions and the general public. While there are great benefits to having content available in digital form, digital objects can be extremely
Kate Wittenberg, Sarah Glasser, Amy Kirchhoff, Sheila Morrissey, Stephanie Orphan   +4 more
doaj   +1 more source