Results 51 to 60 of about 269,061 (300)
Trustworthy 100-Year Digital Objects: Durable Encoding for When It's Too Late to Ask [PDF]
, 2004 How can an author store digital information so that it will be reliably intelligible, even years later when he is no longer available to answer questions?
Gladney, H.M.
core +1 more source
Heritage ScienceHistorical figures have important significance worldwide. This paper introduces the concept of historical Geographical Information System (HGIS) using the lives of two personalities from Chinese history as case studies: Su Shi, a literary figure of the ...
Jing Fu +5 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Evolving Digital Preservation Appraisal Criteria and Selection
Preservation, Digital Technology & CultureThis paper expands the 2018 article “Approaching Appraisal: Framing Criteria for Selecting Digital Content for Preservation” with an examination, review, and discussion.
Tallman Nathan +4 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
QEMU - A Crucial Building Block in Digital Preservation Strategies [PDF]
, 2011 Emulation as long-term preservation strategy depends on usable, reliable and sustainable emulators to preserve old or obsolete original digital environments.
Rechert, Klaus +2 more
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Digital Preservation Services : State of the Art Analysis [PDF]
, 2012 Research report funded by the DC-NET project.An overview of the state of the art in service provision for digital preservation and curation. Its focus is on the areas where bridging the gaps is needed between e-Infrastructures and efficient and forward ...
Dobreva, Milena, Ruusalepp, Raivo
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Digital Preservation of Geospatial Data [PDF]
Library Trends, 2006 The selection, acquisition, and management of digital data are now part and parcel of the work librarians handle on a day-to-day basis. While much thought goes into this work, little consideration may be given to the long-term preservation of the collected data.
Erwin, Tracey +2 more
openaire +1 more source