Results 51 to 60 of about 37,825,652 (272)
The Significance of Storage in the ‘Cost of Risk’ of Digital Preservation [PDF]
, 2008 As storage costs drop, storage is becoming the lowest cost in a digital repository – and the biggest risk. We examine current modelling of costs and risks in digital preservation, concentrating on the Total Cost of Risk when using digital storage systems
Addis, Matthew +2 more
core +2 more sources
Analysis of Nature-Inspired Algorithms for Long-Term Digital Preservation
Mathematics, 2021 Digital preservation is a research area devoted to keeping digital assets preserved and usable for many years. Out of the many approaches to digital preservation, the present research article follows a new object-centered digital preservation paradigm ...
Andres El-Fakdi, Josep Lluis de la Rosa
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Digital preservation in the context of institutional repositories [PDF]
, 2006 Type of paper: General review Purpose of this paper: To discuss the issues and challenges of digital preservation facing institutional repositories and to illustrate JISC’s view on institutional repositories and its key initiatives in helping UK ...
Hockx-Yu, Helen
core +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
A Future Emulation and Automation Research Agenda [PDF]
, 2010 After significant research and proven usefulness especially for complex, dynamic and interactive objects emulation is not widely adapted in digital preservation at all.
Dirk von Suchodoletz +1 more
core +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Digital Preservation Services : State of the Art Analysis [PDF]
, 2012 Research report funded by the DC-NET project.An overview of the state of the art in service provision for digital preservation and curation. Its focus is on the areas where bridging the gaps is needed between e-Infrastructures and efficient and forward ...
Dobreva, Milena, Ruusalepp, Raivo
core
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source