Results 41 to 50 of about 37,825,652 (272)

2014-2015 Digital Preservation Community Survey

open access: yes, 2015
The OPF (Open Preservation Foundation) conducted the 2014/2015 community survey between October 2014 and January 2015 and the results provide a detailed picture of the digital preservation landscape at that time.
Open Preservation Foundation
core   +1 more source

Conceptual Paper: Digital Preservation Strategies in Archival Institution

open access: yesMATEC Web of Conferences, 2018
In this paper, the overall overview of concept of preservation regardless if it is preservation of physical records/archives or digital records/archives is discussed. The concept of the preservation discussed includes preventive preservation, restorative
Ismail Adila, Bullah Affandy Habee
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo   +9 more
wiley   +1 more source

Digital preservation practices in academic libraries in South Africa in the wake of the digital revolution

open access: yesSouth African Journal of Information Management, 2019
Background: The preservation of digital resources in academic institutions in South Africa is an imperative because of the proliferation of digital resources and the realities of the digital revolution. The study focused on digital preservation practices
Tlou M. Masenya, Patrick Ngulube
doaj   +1 more source

The National Digital Information Infrastructure and Preservation Program (NDIIPP) and its Implications for a Research Agenda for Digital Preservation [PDF]

open access: yes, 2002
Legislation enacted by the U.S. Congress in December 2000 allocates funding to the Library of Congress to lead the National Digital Information Infrastructure and Preservation Program (NDIIPP). The collaborative initiative is focused on materials created
Campbell, Laura
core   +1 more source

Preservation in the Age of Google: Digitization, Digital Preservation, and Dilemmas [PDF]

open access: yesThe Library Quarterly, 2010
The cultural heritage preservation community now functions largely within the environment of digital technologies. This article begins by juxtaposing definitions of the terms “digitization for preservation” and “digital preservation” within a sociotechnical environment for which Google serves as a relevant metaphor.
openaire   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Technology responsiveness for digital preservation: a model [PDF]

open access: yes, 2009
Digital preservation may be defined as the cumulative actions undertaken by an organisation or individual to ensure that digital content is usable across generations of information technology.
McGovern, N.Y.
core  

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