Results 51 to 60 of about 1,072,177 (304)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Digital reference services: an overview

open access: yesInformation Impact: Journal of Information and Knowledge Management, 2017
Technological development in the world has brought many changes to libraries and their service deliveries. Many Libraries are trying to improve on their services by moving from face to face interaction to a digital environment. In this era of information explosion, many people rely on the internet for information and less people approach the Reference ...
openaire   +3 more sources

School Librarians, Informal Learning and Digital Reference Services

open access: yesIASL Annual Conference Proceedings, 2021
Digital reference services support informal learning, and integrate it with formal education. Such services can promote the literacy of K-12 students by cultivating children’s desires to learn outside the classroom. Yet few school libraries offer digital reference services to students.
Joanne Silverstein, Sarah Webb
openaire   +2 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu   +14 more
wiley   +1 more source

Provision of digital reference services in academic libraries in Kenya: a review

open access: yesRegional Journal of Information and Knowledge Management, 2017
Rationale of the study - The popularity of internet as an avenue of communication and source of information has led to decreasing numbers of in-person reference transaction in academic libraries.
James M. Tutu
doaj  

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

El servicio de referencia en la biblioteca digital Reference service in the digital library

open access: yesInvestigación Bibliotecológica: Archivonomía, Bibliotecología e Información, 2005
El servicio de referencia se muestra como uno de los servicios más importantes de la biblioteca digital. A grosso modo, se presenta en el artículo un bosquejo histórico del surgimiento del servicio, su concepto y sus características, así como la ...
Georgina Araceli Torres Vargas   +1 more
doaj  

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Virtual reference services : connecting users with experts and supporting the development of skills [PDF]

open access: yes, 2002
Virtual reference - a service that allows librarians and patrons to communicate with each other in real time through the Internet by e-mail, chat or instant messaging - is currently a hot topic in libraries.
Bakker, Trix
core   +3 more sources

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

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