Results 11 to 20 of about 41,229 (153)
Cybrarians Journal, 2009 A study on data repositories. The study addresses the definition of data repositories, then defines their most important characteristics, then the study presents the steps for creating data repositories, then the study discusses storing data in ...
Ahmed Abdallah
doaj +1 more source
Cybrarians Journal, 2019 Nowadays, institutional digital repositories have become an imperative necessity for every university institution that seeks to ensure the management, organization, storage and long-term preservation of its digital assets, intellectual production and
Wessam Ben Ghida
doaj +1 more source
Digital Repository Certification
, 2005 Peer ...
Dobratz, Susanne, Schoger, Astrid
openaire +3 more sources
Digital Archive Policies and Trusted Digital Repositories
International Journal of Digital Curation, 2008 The MIT Libraries, the San Diego Supercomputer Center, and the University of California San Diego Libraries are conducting the PLEDGE Project to determine the set of policies that affect operational digital preservation archives and to develop ...
MacKenzie Smith, Reagan Moore
doaj +8 more sources
Ingeniería e Investigación, 2014 Presently, the most notable challenges associated with repositories in resolving problems of searches of digital resources, lie in providing an understanding of resource classification according to a knowledge representation scheme and the relationship ...
Paulo Alonso Gaona García +2 more
doaj +1 more source
Analysis of computational vulnerabilities in digital repositories
Biblios, 2015 Objective. Demonstrates the results of research that aimed to analyze the computational vulnerabilities of digital directories in public Universities. Argues the relevance of information in contemporary societies like an invaluable resource, emphasizing ...
Valdete Fernandes Belarmino +1 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source