Results 81 to 90 of about 46,464 (262)
Simulation and Validation of Porosity and Permeability of Synthetic and Real Rock Models Using Three-Dimensional Printing and Digital Rock Physics. [PDF]
ACS Omega, 2021 Ibrahim ER +3 more
europepmc +1 more source
Advanced Science, EarlyView.A developmentally guided protocol reproducibly specifies EN1‐positive ventral midbrain dopaminergic (vmDA) progenitors from human pluripotent stem cells and yields functional vmDA neurons. Optogenetic induction of α‐synuclein aggregation elicits selective degeneration of TH‐positive neurons in 2D cultures and 3D neurospheroids, while transplanted ...
Heechang Moon +12 more
wiley +1 more source
Journal of Geophysical Research: Machine Learning and ComputationThe composition, microstructure, and physical behavior of rock at the core‐to‐pore scale are commonly visualized and characterized using 3D X‐ray microcomputed tomography (micro‐CT). However, a key geophysical problem in micro‐CT rock characterization is
Kunning Tang +6 more
doaj +1 more source
Advanced Science, EarlyView.Scalable synthesis of single‐crystal mid‐nickel cathodes demands precise kinetic control over competing densification and grain growth. Oxygen partial pressure emerges as a quantitative descriptor of effective grain‐boundary mobility, acting through changes in the apparent sintering activation barrier.
Hyeonho Park +9 more
wiley +1 more source
LigHTS: Biomimetic Hydrogel Photo‐Fabrication for Imaging‐Based Ultra‐High‐Throughput Screening
Advanced Science, EarlyView.LigHTS removes a key bottleneck for ultra‐high‐throughput screening (UHTS) by enabling biomimetic hydrogel microenvironments to be manufactured directly in standard multiwell plates. A single, collimated UV exposure with formulation‐tuned light penetration patterns an entire plate with UHTS‐grade uniformity (<20% CV), producing structured GelMA films ...
Alessandro Enrico +7 more
wiley +1 more source
An Effective Method for Digital Rock Reconstruction with Enhanced Pore Connectivity
Applied SciencesDigital rock technology is essential for characterizing the petrophysical properties of tight reservoirs. However, conventional construction methods often yield models with insufficient pore connectivity due to low porosity and complex nanopore ...
Junxian Li, Chuanyou Zhou, Ruoyu Li
doaj +1 more source
Advanced Science, EarlyView.Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao +7 more
wiley +1 more source
Advanced Science, EarlyView.This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun +12 more
wiley +1 more source
Advancements in digital drilling technology for deep engineering: a review
Frontiers in Earth ScienceIn deep engineering, the in-situ measurement of engineering rock properties is a key issue in projects such as energy storage and resource mining. Numerous researches devoted to adopting the digital drilling methods for the in-situ application of deep ...
Keqi Fan
doaj +1 more source
Advanced Science, EarlyView.A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing +9 more
wiley +1 more source