Results 141 to 150 of about 37,778,008 (290)
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
Advanced Science, EarlyView.UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source
Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation
Advanced Science, EarlyView.Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu +10 more
wiley +1 more source
Channels of Digital Scholarship
Calenda, 2022 The general aim of the seminar/discussion, is an exchange of information about the different offerings of our various institutions in the field of digital humanities/scholarship training. Particular matters of interest that have been identified are: the curriculum of each course, how it evolved, and why; if there is a particular emphasis for each ...
openaire +1 more source
USFT Digital Scholarship Services Annual Report: FY 2018-2019 [PDF]
, 2019 This is the annual report for FY 2018-2019, the third full year of ...
Digital Scholarship Services
core
SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer
Advanced Science, EarlyView.Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian +8 more
wiley +1 more source
Research Information Literacy and Digital Scholarship final report, May 2013
, 2013 Rapport "Research Information Literacy and Digital Scholarship (RILADS)" Avril 2013, de Stéphane Goldstein et Charlie Inskip. http://rilads.wordpress.com/2013/06/10/rilads-report/ This document summarises the work to date (Oct 2012 – Apr 2013) on the ...
Digital library
core
Advanced Science, EarlyView.Planar ferroelectric lattices with rationally‐tailored topology and polarization achieve programmable piezoelectric and pyroelectric properties. Analytical modeling, homogenization, and experiments collectively demonstrate enhanced and tunable longitudinal, transverse, and shear piezoelectric responses, together with substantially improved ...
Jiahao Shi +6 more
wiley +1 more source
Advanced Science, EarlyView.Dual‐functional fire‐safe microcapsules are integrated into hierarchical solid polymer electrolytes to provide sequential protection against thermal abuse. The ammonium hydrogen phytate‐modified shell forms a protective char barrier, while the thermally triggered release of perfluoro(2‐methyl‐3‐pentanone) actively suppresses combustion, enabling safer ...
Ziqi Huang +5 more
wiley +1 more source
, 2010 Digital Scholarship 2009 includes four bibliographies: the Scholarly Electronic Publishing Bibliography: 2009 Annual Edition, the Institutional Repository Bibliography, the Electronic Theses and Dissertations Bibliography, and the Google Book Search Bibliography.
openaire +2 more sources
Nonlinear Ion‐Specific Control of Underwater Adhesion by Bottlebrush Polymer Interfaces
Advanced Science, EarlyView.The efficiency of underwater adhesion is modulated by ion‐specific effects. Strongly hydrated Na+ remains separated from the mica surface by its hydration shell, preserving access to binding sites, whereas weakly hydrated K+ can partially dehydrate and occupy ditrigonal cavities.
Chang‐Sheng Wang +10 more
wiley +1 more source