Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Features of digital signal processing algorithms using Galois fields GF(2n+1). [PDF]
Suleimenov IE +2 more
europepmc +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Multi-Scale ConvNeXt for Robust Brain Tumor Segmentation in Multimodal MRI
Vision Transformer (ViT) models are well known for effectively capturing global contextual information through self-attention. In contrast, ConvNeXt’s hierarchical convolutional inductive bias enables the extraction of robust multi-scale features at ...
Jose Luis Lopez-Ramirez +6 more
doaj +1 more source
Generalized Property-Based Encoders and Digital Signal Processing Facilitate Predictive Tasks in Protein Engineering. [PDF]
Medina-Ortiz D +6 more
europepmc +1 more source
RF and digital signal processing for software-defined radio: a multi-standard multi-mode approach
Software-defined radio (SDR) is the hottest area of RF/wireless design, and this title describes SDR concepts, theory, and design principles from the perspective of the signal processing (both on transmission and reception) performed by a SDR system ...
Rouphael, Tony J, Rouphael, Tony J.
core
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Finite-size security of continuous-variable quantum key distribution with digital signal processing. [PDF]
Matsuura T, Maeda K, Sasaki T, Koashi M.
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Sparse representations and sphere decoding for array signal processing
Array processing algorithms are used in many applications for source localization and signal waveform estimation. When the number of snapshots is small and/or the signal-to-noise ratio (SNR) is low, it becomes a challenge to discriminate closely-spaced ...
T. Yardibi +7 more
core +1 more source

