Results 81 to 90 of about 297,567 (266)

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi   +8 more
wiley   +1 more source

Multi-Scale ConvNeXt for Robust Brain Tumor Segmentation in Multimodal MRI

open access: yesTechnologies
Vision Transformer (ViT) models are well known for effectively capturing global contextual information through self-attention. In contrast, ConvNeXt’s hierarchical convolutional inductive bias enables the extraction of robust multi-scale features at ...
Jose Luis Lopez-Ramirez   +6 more
doaj   +1 more source

Generalized Property-Based Encoders and Digital Signal Processing Facilitate Predictive Tasks in Protein Engineering. [PDF]

open access: yesFront Mol Biosci, 2022
Medina-Ortiz D   +6 more
europepmc   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

Brain Tumor Segmentation from Optimal MRI Slices Using a Lightweight U-Net

open access: yesTechnologies
The timely detection and accurate localization of brain tumors is crucial in preserving people’s quality of life. Thankfully, intelligent computational systems have proven invaluable in addressing these challenges.
Fernando Daniel Hernandez-Gutierrez   +7 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Concurrent Direct Inter-ONU and Upstream Communications in IMDD PONs Incorporating P2MP Flexible Optical Transceivers and Advanced Passive Remote Nodes

open access: yesPhotonics
Driven by a large number of emerging diversified services, in the 5G and beyond era, concurrent direct inter-ONU and upstream communications inside a PON-based mobile access network are highly desirable to provide dynamic, ultra-dense, and fast ONU-to ...
Wei Jin   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy