Results 101 to 110 of about 5,961,169 (319)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Understanding Age-Related Differences in the Development of Digital Communication and Information Skills in Polish Adolescents

Multidisciplinary Journal of School Education, 2023
Research objectives: This study examines the role of digital skills in the personal and social development of young people. It aims to measure and understand these skills among the younger generation, while identifying ways to improve their development.
Jacek Pyżalski, Natalia Walter, Agnieszka Iwanicka   +2 more
doaj   +1 more source

You can lead a horse to water… are clinical students getting the message about the library and information skills support that is available? [PDF]

, 2009
Cambridge University Library is the recipient of a grant from the Arcadia Trust to investigate issues and challenges in delivering academic library services in the digital era.
Edwards-Waller, L, Kuhn, I
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Next Generation User Skills [PDF]

, 2009
The world is awash with statistics on the impact of the web on 21st century living, learning and working. They are accompanied by the pronouncements and predictions of experts from every camp, from those heralding a new brave new world of co-creation and
Kay, David, McGonigle, Bob, Patterson, Walter, Tabbiner, Barbara   +3 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Impact of the Digital Skills on Employability: Cross-Sectional Analysis

Economies
Digital skills are increasingly vital for enhancing employability, as they equip individuals to meet the evolving demands of the modern workforce. Therefore, this paper examines the impact of digital skills on employability, focusing on the influence of ...
Biljana Đorđević, Sandra Milanović Zbiljić, Marija Radosavljević   +2 more
doaj   +1 more source

E-SKILLS IP – MASTERING THE 21ST CENTURY SKILLS [PDF]

, 2015
In this paper we will present the results of a case study carried out with attendees of an Erasmus Intensive Programme (e-skills IP - Competences for Collaboration and Knowledge Sharing in Digital Society), which has promoted the development of 21st ...
Loureiro, Ana
core  

Confronting the scarcity of digital skills among the poor in developing countries

, 2021
Purpose To describe and compare the components of a package of policies to address the scarcity of digital skills in poor countries. The package comprises an increase in the supply of these skills, a choice of technologies that make few demands on them ...
M. James
semanticscholar   +1 more source