Results 61 to 70 of about 396,336 (296)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Human resources consultants: what digital skills?

open access: yes, 2021
The significant changes in the organisational environment and the frequent technological innovations that arose from the industrial revolutions over the centuries have a considerable impact on the labor market.
Silva, Susana   +3 more
core  

Understanding the digital skills of the career development sector [PDF]

open access: yes, 2020
This article summarises the findings of research which examines the digital skills of the career development ...
Moore, Nicki
core  

Identification of HOTS Creative Thinking, Science Process Skills and Digital Literacy in Physics Subject

open access: yesJurnal Penelitian Fisika dan Aplikasinya, 2022
High Order Thinking Skills (HOTS) creative thinking, science process skills and digital literacy of students are important components in learning, especially learning physics.
Astalini Astalini   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Production Efficiency of Advanced Liquid Biofuels: Prospects and Challenges

open access: yesEnergies
Renewable sources are becoming more critical in light of global warming and the recent energy crisis. As a renewable energy source, biofuels may play an essential role in this process, especially in the transport sector. Advanced biofuels provide a great
Tamás Mizik   +2 more
doaj   +1 more source

Digital Skills

open access: yes, 2021
Digital skills constitute one of the five foundational pillars of the Digital Economy for Africa (DE4A) initiative, launched by the World Bank, and are needed to mobilize digital innovations to transform economies, societies and governments in Africa.
Miyamoto, Koji, Bashir, Sajitha
openaire   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Digital Technology and the Skills Shortage [PDF]

open access: yesComputer, 2007
Governments and businesses in many advanced countries complain about the current skills shortage. They blame it for high wages, lowered economic growth, outsourcing, the need to import skilled workers, the failure of medical care, the high rates of car accidents and unemployment, and pretty well any instance of technical malfunction and project failure.
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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