Results 51 to 60 of about 8,788,792 (362)

A universal framework for Space Resource Utilisation (SRU) [PDF]

open access: yes, 2019
Space Resource Utilisation (SRU) or In Situ Resource Utilisation (ISRU) is the use of natural resources from the Moon, Mars and other bodies for use in situ or elsewhere in the Solar System.
Meurisse, A   +19 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Divergent Realities Across the Digital–Material Divide

open access: yesLaw, Technology and Humans, 2020
This article utilises the example of Australia’s social welfare agency ‘Centrelink’ and its Online Compliance Intervention (OCI) program to illustrate the process of digital translation and digital determinations of material reality. The article explains
Elizabeth Englezos
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

أخلاقيات الاتصال بين عصري الإعلام التقليدي والرقمي التباينات، الإشكاليات، الحلول [PDF]

open access: yesالمجلة المصرية لبحوث الإعلام
 هدفت الدراسة إلى تلمس التحولات الأخلاقية التي أصابت بينة العملية الاتصالية في ظل الانتقال من عصر الإعلام التقليدي إلى عصر الإعلام الرقمي. وتلمس انعكاس ذلك على الأطر الأخلاقية التي حكمت كليهما.
محمود يوسف محمد السماسيري
doaj   +1 more source

Criminal Liability for Cybercrimes in the BRICS Countries

open access: yesBRICS Law Journal, 2023
One of the areas of cooperation among the BRICS countries is tackling the misuse of information and communication technologies for criminal activities. Each year, the number of cybercrimes continues to grow.
L. Ivanova
doaj   +1 more source

Digital Space as Necessary and Sufficient Criterion for Economy Digitalization

open access: yes, 2020
Today, the digital space ensures the success of the digitalization of the economy, forms systems thinking about the processes of digital transformation and makes it possible to avoid unpredictable consequences.
V. Yachmeneva, Evgeniy Yachmenev
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Geospatial mapping and prediction of informal settlement growth in Addis Ababa using GIS and logistic regression model

open access: yesDiscover Environment
Informal settlements (ISs), characterized by unauthorized occupation and construction without legal recognition, represent a critical urban challenge in rapidly developing cities like Addis Ababa, Ethiopia, where 23.8% of the urban population resides in ...
Alazer Bergene Bante   +3 more
doaj   +1 more source

From dual digitalization to digital learning space: Exploring the digital transformation of higher education

open access: yesComput. Educ., 2022
Inspired by the fast digitalization during the Covid-19 crisis, we investigate a key aspect of digital transformation of higher education – the emergence of a digital learning space.
B. Bygstad   +3 more
semanticscholar   +1 more source

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