Results 61 to 70 of about 32,563 (195)

The Fourth Age of Political Communication: Democratic decay or the rise of phronetic political communication?

Nordicum-Mediterraneum, 2016
The ‘fourth age’ of political communication is emerging. In the fourth age the logics of media and digitization shapes the public sphere, because algorithms and polarized drama increasingly determine what we become aware of in digital and mass media. The
Peter Aagaard
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Do Digital Systems and Concepts in Modern Public Service Production Have a Negative Impact on Citizens as End-users?

Nordicum-Mediterraneum, 2016
Do digital systems and concepts in modern public service production have a negative impact on citizens as end-users? To answer this research question, we shall first present our theoretical framework ‘the institutional logics perspective’ and show how we
John Storm Pedersen, Jacob Dahl Rendtorff   +1 more
doaj  

Graphene-infused terracotta acoustic sound amplifiers

Scientific Reports
This work introduces a novel approach for enhancing mobile audio performance by incorporating graphene-infused terracotta as an acoustic amplifier. Leveraging the high thermal conductivity and mechanical strength of graphene, this study demonstrates the ...
T. R. Rajalekshmi, Shilpa Pavithran, Rinku Rani Das, Alex James   +3 more
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

TRIZ for Digital Systems Engineering: New Characteristics and Principles Redefined

Systems, 2019
While innovation from the systems engineer is desirable at every step in all phases of systems engineering, there must be a methodology to evaluate alternatives.
Kari Lippert, Robert Cloutier
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Research on Automatic Measurement Method of Three-dimensional Gamma Dose Rate Radiation Field Based on VSLAM

Yuanzineng kexue jishu
To address the need for rapid acquisition of gamma radiation field information in nuclear facility sites and digital radiation protection systems, simultaneous localization and mapping (SLAM) technology was combined with gamma dose detection technology ...
LI Hui1, 2, 3, ,  FAN Qing1,  LI Hua1, 2, 3, ,  LIU Liye1, 2, 3,  CHEN Faguo1, 2, 3,  LI Deyuan1,  ZHAO Yuan1, 2, 3
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source