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Systematic literature review of digital and green transformation of manufacturing SMEs in Europe

Production and Manufacturing Research: An Open Access Journal
The digital and green transformation of the manufacturing industry is gaining attention in research and practice, often referred to as twin transition. However, understanding twin transitions in SMEs is limited.
Anar Abilakimova, Merja Bauters, Abiodun Afolayan Ogunyemi   +2 more
doaj   +1 more source

On the Role of Regulatory Policy on the Business Case for Energy Storage in Both EU and UK Energy Systems: Barriers and Enablers

Energies, 2020
This paper presents a SWOT analysis of the impact of recent EU regulatory changes on the business case for energy storage (ES) using the UK as a case study. ES technologies (such as batteries) are key enablers for increasing the share of renewable energy
Ahmed Gailani, Tracey Crosbie, Maher Al-Greer, Michael Short, Nashwan Dawood   +4 more
doaj   +1 more source

Towards Interpretable Camera and LiDAR Data Fusion for Autonomous Ground Vehicles Localisation

Sensors, 2022
Recent deep learning frameworks draw strong research interest in application of ego-motion estimation as they demonstrate a superior result compared to geometric approaches. However, due to the lack of multimodal datasets, most of these studies primarily
Haileleol Tibebu, Varuna De-Silva, Corentin Artaud, Rafael Pina, Xiyu Shi   +4 more
doaj   +1 more source

Building the case for actionable ethics in digital health research supported by artificial intelligence [PDF]

, 2019
The digital revolution is disrupting the ways in which health research is conducted, and subsequently, changing healthcare. Direct-to-consumer wellness products and mobile apps, pervasive sensor technologies and access to social network data offer ...
Bartlett Ellis, Rebecca J., Nebeker, Camille, Torous, John   +2 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

VNFlow: integration of variational autoencoders and normalizing flows for novel molecular design

Journal of Cheminformatics
Generative Artificial Intelligence is transforming the molecular discovery by enabling exploration of the vast, largely unexplored chemical space. However, current methods, including normalizing flows, struggle to balance the optimization of complex ...
Jiří Hostaš, Mohammad S. Ghaemi, Hang Hu, Junan Lin, Anguang Hu, Hsu K. Ooi   +5 more
doaj   +1 more source

Lifetime Degradation Cost Analysis for Li-Ion Batteries in Capacity Markets using Accurate Physics-Based Models

Energies, 2020
Capacity markets (CM) are energy markets created to ensure energy supply security. Energy storage devices provide services in the CMs. Li-ion batteries are a popular type of energy storage device used in CMs.
Ahmed Gailani, Maher Al-Greer, Michael Short, Tracey Crosbie, Nashwan Dawood   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

An updated Gappy-POD to capture non-parameterized geometrical variation in fluid dynamics problems

Advanced Modeling and Simulation in Engineering Sciences, 2022
In this work, we propose a new method to fill the gap within an incomplete turbulent and incompressible data field in such a way to satisfy the topological and intensity changes of the fluid flow after a non-parameterized geometrical variation in the ...
Nissrine Akkari, Fabien Casenave, David Ryckelynck, Christian Rey   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source