Results 61 to 70 of about 2,184,166 (294)

Empowerment or Engagement? Digital Health Technologies for Mental Healthcare [PDF]

, 2020
We argue that while digital health technologies (e.g. artificial intelligence, smartphones, and virtual reality) present significant opportunities for improving the delivery of healthcare, key concepts that are used to evaluate and understand their ...
A Nelson, A Sen, A Wardrope, ADI Kramer, AFT Winfield, B Friedman, BC Stahl, Christopher Burr, D Bakker, D Hausman, D Lupton, E Chiauzzi, EA Holm, EC Nelson, F Dzogang, F Greaves, F Starkey, G Spencer, J Garcia, J Owens, J Stilgoe, JA Hall, JJ Breedvelt, K Crawford, K Lehavot, KJ Roberts, L Edwards, L Floridi, L Floridi, L Floridi, L Floridi, L Floridi, L Floridi, M Ananny, M Durante, M D’Agostino, M Janssen, M Jirotka, M Sheehan, M Turilli, M-L Schermuly-Haupt, P Borah, P Nagy, R Andorno, R Binns, R Guidotti, R Kenny, R Kukla, RA Calvo, RD McMullan, SE Polykalas, SR Kamens, SR Paige, T Grisso, T Miller, Thomas Lansdall-Welfare, TL Beauchamp, W-W Zhao, WA Anthony, X Chen   +59 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The changing patterns of architectural design education [PDF]

, 2008
Digital technologies have been introduced to students of architecture for over two decades and at present it could be argued that students are producing some of the highest quality designs, and some of the most interesting forms ever to come from ...
Giddings, Bob, Horne, Margaret
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Development of an Early Lung Cancer Diagnosis Method Based on a Neural Network

Computers
Cancer is one of the most lethal diseases in the modern world. Early diagnosis significantly contributes to prolonging the life expectancy of patients. The application of intelligent systems and AI methods is crucial for diagnosing oncological diseases ...
Indira Karymsakova, Dinara Kozhakhmetova, Dariga Bekenova, Danila Ostroukh, Roza Bekbayeva, Lazat Kydyralina, Alina Bugubayeva, Dinara Kurushbayeva   +7 more
doaj   +1 more source

On the state feedback control of inverted pendulum with hysteretic nonlinearity

MATEC Web of Conferences, 2014
In this paper we consider the mathematical model of the inverted pendulum with the hysteretic nonlinearity (in the form of backlash) under state feedback control.
Semenov Mikhail E., Grachikov Dmitry V., Rukavitsyn Anton G., Meleshenko Peter A.   +3 more
doaj   +1 more source

Two-dimensional mathematical model of heat and moisture transfer processes during the natural storage and drying of heterogeneous agricultural products [PDF]

BIO Web of Conferences
Developed a two-dimensional mathematical model of simultaneous heat and moisture transfer processes during the natural storage and drying of heterogeneous agricultural products in open areas.
Shadmanov Istam, Nosirova Zarnigor, Kamolova Umida   +2 more
doaj   +1 more source

Open-source digital technologies for low-cost monitoring of historical constructions [PDF]

, 2017
This paper shows new possibilities of using novel, open-source, low-cost platforms for the structural health monitoring of heritage structures. The objective of the study is to present an assessment of increasingly available open-source digital modeling ...
Basto, Camilo, Chacón Flores, Rolando Antonio, Pelà, Luca   +2 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The pedagogical challenges to collaborative technologies [PDF]

, 2009
Collaborative technologies offer a range of new ways of supporting learning by enabling learners to share and exchange both ideas and their own digital products.
Laurillard, Diana
core   +3 more sources