Results 81 to 90 of about 3,734,160 (288)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Image super-resolution method using a generative adversarial network incorporating attention and residual density

open access: yesScientific Reports
Image super-resolution reconstruction is currently gaining huge attention because of its very promising applications. However, there are still problems such as loss of detailed features and low signal-to-noise ratio. To address this problem, we propose a
Qiong Zhang   +4 more
doaj   +1 more source

Digital Technology and Cultural Policy [PDF]

open access: yes
This paper reviews how digital technology, and the devices and broadband networks associated with it (the Internet, for short), can be expected to a ect the ways in which books, music, the visual arts, libraries and archived cultural heritage (cultural ...
Kieran Healy
core  

Leslislating in the Face of New Technology: Copyright Laws for the Digital Age [PDF]

open access: yes, 1996
This Note discusses the agendas and proposals of different countries with respect to copyright regulation in the digital age. Part I discusses the present state of copyright law in the United States, the United Kingdom, and the European Community. Part I
Morano, Michael F.
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Technology-Enhanced Teaching: A Technology Acceptance Model to Study Teachers’ Intentions to Use Digital Games in the Classroom [PDF]

open access: yes, 2019
This research to practice paper uses a Technology Acceptance Model (TAM) to explore the factors that affect teachers’ intentions to use digital educational games in the classroom.
Anderson, Emma   +3 more
core   +1 more source

Taking time to understand: articulating relationships between technologies and organizations [PDF]

open access: yes, 2010
Dynamic relationships between technologies and organizations are investigated through research on digital visualization technologies and their use in the construction sector.
Whyte, Jennifer
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Beamforming Techniques for Large-N Aperture Arrays

open access: yes, 2010
Beamforming is central to the processing function of all phased arrays and becomes particularly challenging with a large number of antenna element (e.g. >100,000).
Adami, K Zarb   +4 more
core   +1 more source

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