Results 101 to 110 of about 450,796 (317)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Optimizing Virtual Power Plants with Parallel Simulated Annealing on High-Performance Computing

Smart Cities
This work focuses on optimizing the scheduling of virtual power plants (VPPs)—as implemented in the Portuguese national project New Generation Storage (NGS)—to maximize social welfare and enhance energy trading efficiency within modern energy grids.
Ali Abbasi, Filipe Alves, Rui A. Ribeiro, João L. Sobral, Ricardo Rodrigues   +4 more
doaj   +1 more source

Digital Transformation Roadmap - Toolkit v3 [PDF]

, 2023
Digital Transformation RoadmapA guide for African science granting councils to support the development and maintenance of data management systems, with a particular focus on ...
Petersen, I, Davids, M
core  

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

UI/UX design requirements for young stroke survivors: recommendations from the literature

npj Digital Medicine
There is currently no single resource for UI/UX guidelines and design standards that encapsulates all the requirements for young stroke survivors (
Deborah Passey, Hasan Ferdous, Kara Burns, Cecily Gilbert, Emma Power, Tanya Rose, Julie Bernhardt, Vincent Thijs, Daniel Capurro   +8 more
doaj   +1 more source

Impact of digital transformation: assessing the knowledge and adoption of disruptive technologies in a higher education institution

Frontiers in Computer Science
Digital transformation has become a key factor for educational development since it not only involves the integration of disruptive technologies but also the restructuring of the process and cultural adaptation that allows Higher Education Institutions ...
Janet Aquino, Roger Alarcón, Laurita Guevara, Jessie Bravo-Jaico, Nilton Germán, Carlos Valdivia-Salazar, Oscar Serquén, Gisella Luisa Elena Maquen-Niño, Alfonso Tesén-Arroyo   +8 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source