Results 31 to 40 of about 22,284 (219)

A Returnable Transport Item to Integrate Logistics 4.0 and Circular Economy in Pharma Supply Chains

Tehnički Glasnik, 2023
Recent global events, such as the COVID-19 pandemic, the war in Ukraine and the climate crisis, force the pharma logistics sector to rapidly improve their processes and establish more resilient and sustainable medical supply chains. For this purpose, the
Gerald Schneikart, Walter Mayrhofer, Josef Frysak, Clemens Löffler   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Challenges for remote patient monitoring programs in rural and regional areas: a qualitative study

BMC Health Services Research
Background Access to healthcare significantly influences health outcomes, and rural, regional and remote populations face greater challenges in accessing healthcare than urban populations.
Joel Fossouo Tagne, Kara Burns, Teresa O’Brein, Wendy Chapman, Portia Cornell, Kit Huckvale, Ishaan Ameen, Jaclyn Bishop, Alison Buccheri, Jodie Reid, Anna Wong Shee, Marc Budge, Catherine E. Huggins, Anna Peeters, Olivia Metcalf   +14 more
doaj   +1 more source

The urgency of regulating artificial intelligence in relation to cybersecurity and cyber resilience

Cogent Social Sciences
Cybercrime has become a major transnational threat, with ransomware and malware posing serious risks to individuals, governments, and critical infrastructure.
Ahmad M. Ramli, Sigid Suseno, Ranti Fauza Mayana, Ramalinggam Rajamanickam, Rubben Denova Rohmana   +4 more
doaj   +1 more source

Fostering the use of Learning Health Systems through a fellowship program for interprofessional clinicians

Learning Health Systems, 2022
Introduction To address Australian workforce needs, we developed a Learning Healthcare System (LHS) Academy fellowship program for clinicians. In the Academy, fellows complete foundational coursework, an LHS project, and other professional development ...
Sathana Dushyanthen, Meg Perrier, Wendy Chapman, Meredith Layton, Kayley Lyons   +4 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Assessment of Hammer Energy Measurement for the Standard Penetration Test (SPT) Using Pile Driving Analyzer and Kallpa Analyzer Devices in Peru

Sensors
Energy measurement in dynamic penetration tests is key to correctly interpreting test results and ensuring comparable geotechnical data. Although commercial devices are widely used, their high cost limits adoption in developing regions such as Peru ...
Carmen Ortiz, Jorge Alva, José Oliden, Nelly Huarcaya, Grover Riveros, Roberto Raucana   +5 more
doaj   +1 more source

TEE: Real-Time Purchase Prediction Using Time Extended Embeddings for Representing Customer Behavior

Journal of Theoretical and Applied Electronic Commerce Research, 2023
Real-time customer purchase prediction tries to predict which products a customer will buy next. Depending on the approach used, this involves using data such as the customer’s past purchases, his or her search queries, the time spent on a product page ...
Miguel Alves Gomes, Mark Wönkhaus, Philipp Meisen, Tobias Meisen   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source